Trial Outcomes & Findings for Third International Study on Mechanical Ventilation (NCT NCT01093482)

Results Overview

Mortality at discharge from intensive care unit

Recruitment status

COMPLETED

Target enrollment

8151 participants

Primary outcome timeframe

At day 28 after the beginning of mechanical ventilation

Results posted on

2018-03-01

Consecutive patients who required mechanical ventilation for more than 12 hours in the participating intensive care units.

Participant milestones
Measure	Mechanically Ventilated Patients 1. Patients who are admitted to the participating intensive care units and require invasive mechanical ventilation (endotracheal tube or tracheostomy) for more than 12 hours. 2. Patients who are admitted to the participating intensive care units and require non-invasive mechanical ventilation (Bilevel positive airway pressure (BIPAP) or continuous positive airway pressure (CPAP) with nasal or facial mask) for more than 1 hour.
Overall Study STARTED	8151
Overall Study COMPLETED	8151
Overall Study NOT COMPLETED	0

Withdrawal data not reported

Third International Study on Mechanical Ventilation

Baseline characteristics by cohort
Measure	Mechanically Ventilated Patients n=8151 Participants 1. Patients who are admitted to the participating intensive care units and require invasive mechanical ventilation (endotracheal tube or tracheostomy) for more than 12 hours. 2. Patients who are admitted to the participating intensive care units and require non-invasive mechanical ventilation (Bilevel positive airway pressure (BIPAP) or continuous positive airway pressure (CPAP) with nasal or facial mask) for more than 1 hour.
Age, Categorical <=18 years	0 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	4233 Participants n=5 Participants
Age, Categorical >=65 years	3918 Participants n=5 Participants
Age, Continuous	61 years STANDARD_DEVIATION 18 • n=5 Participants
Sex: Female, Male Female	3105 Participants n=5 Participants
Sex: Female, Male Male	5046 Participants n=5 Participants

Timeframe: At day 28 after the beginning of mechanical ventilation

Mortality at discharge from intensive care unit

Outcome measures
Measure	Mechanically Ventilated Patients n=8151 Participants 1. Patients who are admitted to the participating intensive care units and require invasive mechanical ventilation (endotracheal tube or tracheostomy) for more than 12 hours. 2. Patients who are admitted to the participating intensive care units and require non-invasive mechanical ventilation (Bilevel positive airway pressure (BIPAP) or continuous positive airway pressure (CPAP) with nasal or facial mask) for more than 1 hour.
All-cause Mortality	2269 Participants

Serious events: 0 serious events

Other events: 0 other events

Deaths: 2269 deaths

Adverse event data not reported

Adverse event data not reported

VENTILA group

Phone: 34916834982