Functional Neuroimaging of Cortical Plasticity in the Human Visual System

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2009-01-31

Study Completion Date

2015-12-31

Brief Summary

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The study's objective is to measure changes in human visual cortex organization that may arise as a result of injury to the visual pathways. Subjects with retinal or cortical injury will be studied and compared to appropriate controls. Functional magnetic resonance imaging methods are used to monitor cortical topography in time. The main aims of the study are to determine: 1) what are the patterns of cortical reorganization that are seen spontaneously after injury, and 2) whether rehabilitative training can promote adaptive reorganization enhancing recovery.

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Detailed Description

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Conditions

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Stroke Blindness Vision

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Stable lesion of the visual pathways resulting in a visual field scotoma.

Exclusion Criteria

* Inability to undergo magnetic resonance imaging,
* Inability to comply with basic instructions,
* Inability to perform the behavioral tasks required,
* Patients with chronic progressive neurological or psychiatric disorders,
* Patients that are pregnant, or breast feeding.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes