Malaria Survey in Mbarara District, Uganda 2010

NCT ID: NCT01062386

Last Updated: 2011-08-12

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 2320 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-01-31
• Study Completion Date: 2010-07-31

Brief Summary

Malaria is one of the major public health problems in Sub-Saharan Africa. In response to this threat, Roll Back Malaria (RBM) has rolled back a strategy using ACT as first line therapy for malaria episode, a wide distribution of Insecticide Treated Bednet (ITN), intermittent presumptive treatment of pregnant women and indoor residual spraying. Recent epidemiological observations suggested a decline in malaria prevalence in some countries but further evidences are still needed to confirm this evolution. The RBM strategy requires the use of reliable rapid diagnostic test (RDT) for which an operational assessment is necessary. Lastly, home-based management of malaria is also an important compound of this strategy. However, a better understanding of the actual use of antimalarial drugs, of the use of bednet and of the barrier to the use of health care is important to implement good quality strategies for malaria control.

This study is a cross-sectional community based survey made of two rounds (one in January 2010 and the second in June 2010). The general objective is to measure the prevalence of infection with Plasmodium falciparum at two periods of the year (at the moment of lowest and highest transmission based on the seasonal rainfalls) and to compare it with the prevalence estimated in 2004 after the rainy season for the same area. Specific objective are the estimation of the prevalence by age stratum, the analysis of the geographical distribution of the infection, the description of the parasitological characteristics, the assessment of three RDT, the description and the analysis of the prevention and care seek behaviours related to malaria.

The study area is the great Mbarara district located in south-west of Uganda. A three-stage cluster sampling method will be used. Spatial information will be collected with global positioning system and imported to Geographical Information System. Behaviour information will be collected through face to face interview.

Conditions

Malaria

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

• Males and females
• Ages 1 month to 59 months

Exclusion Criteria

• None

• Minimum Eligible Age: 1 Month
• Maximum Eligible Age: 59 Months
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Medecins Sans Frontieres, Netherlands

OTHER

Sponsor Role: collaborator

Epicentre

OTHER

Sponsor Role: lead

Responsible Party

Epicentre

Principal Investigators

Carolyn Nabasumba

Role: PRINCIPAL_INVESTIGATOR

Epicentre

Locations

Greater Mbarara district

Mbarara, Mbarara, Uganda

Countries

Uganda

Other Identifiers

Epicentre/Mba/2010/MalPrev

Identifier Type: -

Identifier Source: org_study_id