Comparative Clinical Trial of Lornoxicam to Diclofenac in Patients of Osteoarthritis of Knee Joint.

NCT ID: NCT01055470

Last Updated: 2010-01-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-12-31

Study Completion Date

2009-06-30

Brief Summary

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The purpose of this study was to compare the pain relieving action of the lornoxicam and diclofenac in patients of OA knee.

Detailed Description

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Conditions

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Osteoarthritis of Knee Joint

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Diclofenac

Tab.Diclofenac 50 mg ,Orally, 12 hrly in morning and in evening after taking food for 3 months.

Group Type ACTIVE_COMPARATOR

Diclofenac

Intervention Type DRUG

Tab. Diclofenac 50 mg 12 hrly, orally, in morning and in evening after taking food for 3 months.

Lornoxicam

Tab. Lornoxicam 4 mg , orally, 8 hourly after taking food in morning , in noon and evening for 3 months.

Group Type EXPERIMENTAL

Lornoxicam

Intervention Type DRUG

Tab. Lornoxicam 4 mg , orally, 8 hourly after taking food in morning , in noon and evening for 3 months.

Interventions

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Diclofenac

Tab. Diclofenac 50 mg 12 hrly, orally, in morning and in evening after taking food for 3 months.

Intervention Type DRUG

Lornoxicam

Tab. Lornoxicam 4 mg , orally, 8 hourly after taking food in morning , in noon and evening for 3 months.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Newly diagnosed patient aged between 25 to 65 yrs of either gender suffering from osteoarthritis of knee according to criteria given by American College of Rheumatology
* Informed consent obtained from the patient.

Exclusion Criteria

* Patients with any other systemic llness,
* Patients with pregnancy and lactation,
* Patients taking other drugs like lithium\[4\], digoxin, methotrexate, anticoagulants, antidiabetics, diuretics,
* Patients with H/O hypersensitivity to NSAIDs,
* Patients who had consumed any analgesics in last 1 month
Minimum Eligible Age

25 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Government Medical College, Bhavnagar

OTHER

Sponsor Role lead

Responsible Party

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Government Medical College, Bhavnagar-364001, Gujarat, India

Principal Investigators

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Dr.Vishalkumar Kishorbhai Vadgama, M.B;B.S.

Role: PRINCIPAL_INVESTIGATOR

Department of Pharmacology, Government Medical College, Bhavnagar-364001, Gujarat, India

Dr. Chandrabhanu Rajkishore Tripathi, M.D. (Pharmacology)

Role: STUDY_CHAIR

Proffessor and Head, Department of Pharmacology, Government Medical College, Bhavnagar-364001, Gujarat, India

Locations

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Sir Takthasinhji General Hospital

Bhavnagar, Gujarat, India

Site Status

Countries

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India

Other Identifiers

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Pharmacol no.02 /2008 Research

Identifier Type: -

Identifier Source: org_study_id

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