Propofol Versus Ketamine for Moderate Procedural Sedation in the Emergency Department (ED)

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-07-31

Study Completion Date

2009-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is a clinical trial of moderate sedation with propofol versus moderate sedation with ketamine for procedural sedation in the Emergency Department.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation

NCT01260662

Procedural Sedation

COMPLETED PHASE4

Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation

NCT00997126

Sedation

COMPLETED PHASE4

Moderate Versus Deep Procedural Sedation With Propofol in the Emergency Department

NCT02404610

Pain

COMPLETED PHASE4

Combination Ketamine and Propofol vs Propofol for Emergency Department Sedation: A Prospective Randomized Trial

NCT01269307

Sedation

COMPLETED NA

Ketamine Versus Fentanyl as an Adjunct to Propofol-Assisted Emergency Department Procedural Sedation

NCT00137085

Fractures Dislocations Abscess +2 more

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Sedation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Propofol

propofol 1 milligram per kilogram intravenous bolus followed by 0.5 millligrams per kilogram as needed for mooderate procedural sedation

Group Type ACTIVE_COMPARATOR

propofol

Intervention Type DRUG

propofol 1 millgram per kilogram intravenous bolus followed by 0.5 milligrams per kilogram as needed for moderate procedural sedation

Ketamine

ketamine 1 milligram per kilogram followed by 0.5 millgram per kilogram as needed for moderate procedural sedation

Group Type ACTIVE_COMPARATOR

Ketamine

Intervention Type DRUG

ketamine milligram per kilogram followed by 0.5 milligrams per kilogram as need for moderate procedural sedation

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

propofol

propofol 1 millgram per kilogram intravenous bolus followed by 0.5 milligrams per kilogram as needed for moderate procedural sedation

Intervention Type DRUG

Ketamine

ketamine milligram per kilogram followed by 0.5 milligrams per kilogram as need for moderate procedural sedation

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients who require moderate procedural sedation with propofol in the ED

Exclusion Criteria

* age \> 17 years
* pregnant
* intoxicated
* cannot give informed consent
* allergy to ketamine or propofol
* patient will require deep procedural sedation
* ASA physical status score \> 2

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No