A Long Term Follow up Study of Patients Who Have Complete Clearance of Their Actinic Keratosis (AK) Lesions at the Day 57 Visit in the PEP005-028 Study

NCT ID: NCT00989313

Last Updated: 2015-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

43 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-09-30

Study Completion Date

2010-10-31

Brief Summary

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This study is designed to follow up patients, who have participated in the PEP005-028 study and observed complete clearance of their Actinic Keratosis (AK) lesions, over a 12 month period to assess both recurrence of AK lesions and long term safety in the selected treatment area.

Detailed Description

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Conditions

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Actinic Keratosis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Lesion count

Intervention Type DRUG

Lesion count in area treated by study drug in a prior study. No drug will be applied during this long-term follow up study. Drug was applied during the primary study.

Interventions

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Lesion count

Lesion count in area treated by study drug in a prior study. No drug will be applied during this long-term follow up study. Drug was applied during the primary study.

Intervention Type DRUG

Other Intervention Names

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AK lesion recurrence

Eligibility Criteria

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Inclusion Criteria

* Patient has provided informed consent documented by signing the Informed Consent Form (ICF) prior to any study-related procedures
* Patient achieved complete clearance of AK lesions (lesion count of 0) in the selected treatment area at the Day 57 visit in the following Peplin AK clinical Study: PEP005-028

Exclusion

* Concurrent participation in another research study which would involve the selected treatment area (except for any post-study follow-up visits for previous Peplin AK study)
* Early termination from study PEP005-028
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peplin

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Burke Pharmaceutical Research

Hot Springs, Arizona, United States

Site Status

Skin Surgery Medical Group Inc.

San Diego, California, United States

Site Status

Atlanta Dermatology, Vein & Research Center, LLC

Alpharetta, Georgia, United States

Site Status

Altman Dermatology Associates

Arlington Heights, Illinois, United States

Site Status

Glazer Dermatology

Buffalo Grove, Illinois, United States

Site Status

Deaconess Clinic Downtown

Evansville, Indiana, United States

Site Status

Dawes Fretzin Clinical Research Group, LLC

Indianapolis, Indiana, United States

Site Status

Skin Specialists, PC

Omaha, Nebraska, United States

Site Status

Karl G. Heine Dermatology

Henderson, Nevada, United States

Site Status

Group Health Associates

Cincinnati, Ohio, United States

Site Status

DermResearch, Inc.

Austin, Texas, United States

Site Status

Suzanne Bruce and Associates, PA, The Center for Skin Research

Houston, Texas, United States

Site Status

Dermatology Clinical Research Center of San Antonio

San Antonio, Texas, United States

Site Status

Dermatology Associates of Tyler

Tyler, Texas, United States

Site Status

Dermatology Research Centre

Salt Lake City, Utah, United States

Site Status

The Education and Research Foundation

Lynchburg, Virginia, United States

Site Status

Virginia Clinical Research, Inc

Norfolk, Virginia, United States

Site Status

Countries

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United States

References

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Lebwohl M, Shumack S, Stein Gold L, Melgaard A, Larsson T, Tyring SK. Long-term follow-up study of ingenol mebutate gel for the treatment of actinic keratoses. JAMA Dermatol. 2013 Jun;149(6):666-70. doi: 10.1001/jamadermatol.2013.2766.

Reference Type DERIVED
PMID: 23553119 (View on PubMed)

Related Links

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http://www.fda.gov

Food and Drug Authority

Other Identifiers

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PEP005-032

Identifier Type: -

Identifier Source: org_study_id

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