Ovarian Cancer Risk Estimation in Patients With Pelvic Mass

NCT ID: NCT00987649

Last Updated: 2011-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

512 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-10-31

Study Completion Date

2010-09-30

Brief Summary

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The purpose of this study is to determine whether the Risk of Ovarian Cancer Algorithm (ROMA) is effective in the determination of a woman's risk of cancer when she is scheduled to have surgery to remove a pelvic mass.

After Informed Consent is obtained, an Initial Cancer Risk Assessment will be made. A blood sample will be collected within 30 days of the surgical procedure. Results of the surgical procedure will be collected and analyzed against the CA125 and HE4 results used in the calculation of the ROMA.

Detailed Description

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Conditions

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Adnexal Mass Ovarian Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Female, age ≥ 18 years
* Adnexal mass present documented by imaging
* Scheduled to undergo surgery based on a finding of adnexal mass (defined as a simple, complex or a solid ovarian cyst/or any mass in pelvis)
* Able to understand and willing to provide Informed Consent

Exclusion Criteria

* Previous history of ovarian cancer
* Previous history of bilateral oophorectomy
* Currently known to be pregnant
* Unable to provide informed consent
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Advanced Clinical Research Services, LLC

OTHER

Sponsor Role collaborator

ReSearch Pharmaceutical Services, Inc.

INDUSTRY

Sponsor Role collaborator

Fujirebio Diagnostics, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Fujirebio Diagnostics, Inc.

Principal Investigators

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Richard Moore, MD, FACOG, FACS

Role: PRINCIPAL_INVESTIGATOR

Women & Infants Hospital Rhode Island

Locations

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Scripps Clinic Carmel Valley

San Diego, California, United States

Site Status

Women's Clinic of Northern Colorado

Fort Collins, Colorado, United States

Site Status

OB/GYN Specialists of the Palm Beaches

Jupiter, Florida, United States

Site Status

University of South Florida Medical Center

Tampa, Florida, United States

Site Status

Woman's Hospital

Baton Rouge, Louisiana, United States

Site Status

Weill Medical College of Cornell University

New York, New York, United States

Site Status

New Hanover Regional Medical Center

Wilmington, North Carolina, United States

Site Status

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, United States

Site Status

Geisinger Medical Center

Danville, Pennsylvania, United States

Site Status

Women & Infants Hospital Rhode Island

Providence, Rhode Island, United States

Site Status

Chattanooga GYN-ONCOLOGY

Chattanooga, Tennessee, United States

Site Status

Jackson Clinic

Jackson, Tennessee, United States

Site Status

Adams Patterson Gynecology & Obstetrics

Memphis, Tennessee, United States

Site Status

Countries

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United States

References

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Moore RG, Hawkins DM, Miller MC, Landrum LM, Gajewski W, Ball JJ, Allard WJ, Skates SJ. Combining clinical assessment and the Risk of Ovarian Malignancy Algorithm for the prediction of ovarian cancer. Gynecol Oncol. 2014 Dec;135(3):547-51. doi: 10.1016/j.ygyno.2014.10.017. Epub 2014 Oct 23.

Reference Type DERIVED
PMID: 25449569 (View on PubMed)

Related Links

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http://www.fdi.com

Information related to Fujirebio Diagnostics, Inc.

Other Identifiers

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FDI-15

Identifier Type: -

Identifier Source: org_study_id

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