Evaluation of Pathwork Tissue of Origin (TOO) Test for Human Malignancies

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

2 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-02-29

Study Completion Date

2009-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The pathworks tissue of origin test is a microarray-based test with the goal of identifying the tissue of origin in patients with metastatic tumors of unknown primary site.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

A Prospective Study of Clinical Outcomes for the Pathwork Tissue of Origin Test

NCT01649453

Neoplasm Metastasis

TERMINATED

Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment

NCT05600933

Solid Tumors Hematologic Malignancy Gastrointestinal Cancer +5 more

ENROLLING_BY_INVITATION

Clinical and Pathologic Studies in Neuroendocrine Tumors

NCT00657332

Carcinoid Tumor Neuroendocrine Tumors

WITHDRAWN

Identifying Tissue-of-origin in Transplant Patients and Patients with Malignancies.

NCT06703853

Malignancies

ACTIVE_NOT_RECRUITING

Genomic Profiling in Recommending Treatment for Patients With Metastatic Solid Tumors

NCT02215928

Unspecified Adult Solid Tumor, Protocol Specific

RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Neoplasm Metastasis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Pathwork TOO test

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

2 Patients with a diagnosis of malignancy established by pathologic review of H\&E staining of tumor biopsy or tumor resection without definitive determination of tissue of origin as assessed by the PI. Samples must have been obtained within three months of enrollment, or the patient must still be under active evaluation for tissue of origin at the time of enrollment. There are no limitations on prior therapy and time from last prior therapy.

Exclusion Criteria

2 There are no exclusion requirements due to co-morbid disease or incurrent illness, as needed.

3 Pregnancy or nursing participants will not be excluded from the study.

4 Patients with a diagnosis of leukemia including acute myelogenous leukemia, acute lymphocytic leukemia, hairy cell leukemia, chronic myelogenous leukemia and chronic lymphocytic leukemia are excluded from enrollment on this study. The TOO test does not cover these diagnoses.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No