Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
40 participants
INTERVENTIONAL
2009-08-31
2010-06-30
Brief Summary
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The hypothesis is that the investigators method (rebreathing) will be faster than the current method of administering Oxygen.
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Detailed Description
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Asking someone to breathe back in the air they have just exhaled seems, on the face of it, to be pointless at best. But doing just that for a very short time will make the person breathe harder. Then when you give them pure oxygen, they will breathe it in really deeply and this might make the preoxygenation quicker. That's the theory. To test it we plan to ask 40 healthy people to do the standard preoxygenation, then try our new way. We won't be giving anaesthetic, just the oxygen.
The hypothesis is that our new method will be quicker than the existing one.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
SUPPORTIVE_CARE
DOUBLE
Study Groups
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Rebreathing method of preoxygenation
Subjects will breathe Oxygen through a close fitting mask, but the flow will be low so that they rebreathe some of their expired air. After 30 seconds, the flow will be turned up so that they will breathe 100% Oxygen.
Oxygen
Experimental: Low flow Oxygen for 30 seconds then high flow for 3.5 minutes. Active comparator: High flow Oxygen for 4 minutes.
T method of preoxygenation
Tidal breathing of 100% oxygen through a well fitting facemask, for 4 minutes.
Oxygen
Experimental: Low flow Oxygen for 30 seconds then high flow for 3.5 minutes. Active comparator: High flow Oxygen for 4 minutes.
Interventions
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Oxygen
Experimental: Low flow Oxygen for 30 seconds then high flow for 3.5 minutes. Active comparator: High flow Oxygen for 4 minutes.
Eligibility Criteria
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Inclusion Criteria
* Non-smoker
* No chronic cardiorespiratory or neuromuscular illness
* No intercurrent illness
Exclusion Criteria
18 Years
40 Years
MALE
Yes
Sponsors
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National Health Service, United Kingdom
OTHER_GOV
Responsible Party
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National Health Service
Principal Investigators
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John Glen, MBChB
Role: PRINCIPAL_INVESTIGATOR
UK National Health Service
Locations
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Victoria Infirmary
Glasgow, Glasgow, United Kingdom
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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08/S071038
Identifier Type: -
Identifier Source: org_study_id
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