Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
PHASE4
20 participants
INTERVENTIONAL
2010-01-31
2011-12-31
Brief Summary
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The principal aim of the study is to compare the speed of onset and the time of recovery of motor blockage achieved by lidocaine and buprenorphine, respectively. The investigators hypothesize that the blocking capacity of buprenorphine is equal to the one of lidocaine.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
DOUBLE
Interventions
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buprenorphine
intradermal injection
Eligibility Criteria
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Inclusion Criteria
2. Age: 18 - 65 years
3. Weight: 50-100kg
4. Height: 155-195cm
5. Signed and dated informed consent
6. Sufficient command of German language
Exclusion Criteria
2. Vulnerable subjects (intellectually or mental impaired)
3. Known hypersensitivity to class of drugs or the investigational product
4. Drug abuse
5. Known peripheral neuropathies
6. Diabetes mellitus
7. Chronic alcohol consumption
8. Congestive heart disease
9. Participants of other studies during study period
18 Years
70 Years
MALE
Yes
Sponsors
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University of Zurich
OTHER
Responsible Party
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Principal Investigators
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Konrad Maurer, MD
Role: PRINCIPAL_INVESTIGATOR
Oberarzt Institute of Anesthesiology
Locations
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University Hospital Zurich, Institut of Anaesthesiology
Zurich, Canton of Zurich, Switzerland
Countries
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Other Identifiers
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Stv 2/2009
Identifier Type: -
Identifier Source: org_study_id
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