Multicentric Evaluation of Two Telematics Systems in Type 2 Diabetic Patients in Failure of Oral Treatment and Having to Start Treatment by Basal Insulin

NCT ID: NCT00937703

Last Updated: 2013-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-12-31

Study Completion Date

2013-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

TELEDIAB-2 is a national, multicenter, controlled, randomised trial. The primary objective of the study is to show that during the initiation of a basal insulin treatment , a computerized decision-making system of adaptation of the insulin, coupled to a distance follow-up (thanks to PDAphone or an interactive vocal server (IVS)), is able to improve metabolic control at the end of 4 mouths as compared with conventional care.

Main judgment criteria: comparison of HbA1c means of the 2 groups profiting from a telemonitoring system compared to the reference group at 4 months.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Secondary objectives :

1. \- To compare the 2 methods of telemonitoring employed.
2. \- To evaluate the speed of the glycemic attack of the objective to the rising, according to the method of follow-up employed.
3. \- To evaluate the satisfaction of the patients and the doctors with respect to systems of telemonitoring, and improvement of the quality of life (DQOL).

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

TYPE 2 DIABETES

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group1: Control group

face to face visit à T4mounths

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DEVICE

paper support for glycaemia face to face visit at T4mounths

Group2: IVS Group

face to face visit at T4mounths plus telephone visits each 2 weeks

Group Type ACTIVE_COMPARATOR

IVS

Intervention Type DEVICE

patients transmit their glycaemia to the IVS, which advises them the insulin amount recommended by their physician in this situation.

Face to face visit at T4mounths plus telephone visits each 2 weeks.

Group3: PDAphone group

PDA system face to face visit at T4mounths plus telephone visits each 2 weeks

Group Type ACTIVE_COMPARATOR

PDAphone

Intervention Type DEVICE

Patients will receive PDA phone system. They will hace face to face visit at T4mounths and telephone visits each 2 weeks

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

placebo

paper support for glycaemia face to face visit at T4mounths

Intervention Type DEVICE

IVS

patients transmit their glycaemia to the IVS, which advises them the insulin amount recommended by their physician in this situation.

Face to face visit at T4mounths plus telephone visits each 2 weeks.

Intervention Type DEVICE

PDAphone

Patients will receive PDA phone system. They will hace face to face visit at T4mounths and telephone visits each 2 weeks

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Type 2 diabetes since more than 3 years and claiming a strict balance glycemic;
* Patients treated since at least 3 months, by metformin and secreting insulinic (KNOWN or glinide);
* Patients uncontrolled with HbA1c ≥ 7.5% and \< 10% at the inclusion.
* BMI \< 40 ;
* Patients requiring a insulin treatment
* Patients agree to start a slow insulin treatment
* Patients already practising the glycemic self-monitoring or agree to learn it and practise it;
* Patients able to include/understand operation and to use the PDA-phone and/or the SVI;
* Patient not taking part in another biomedical research study
* Patients agree to carry out at least 2 finger sticks per day;
* More than 18 years, there is no higher age limit.

Exclusion Criteria

* Patients introducing any evolutionary pathology associated and not stabilized, exhibitor with an uncontrolled diabetes during the year to come;
* Patients in a situation which justifies of a clinical follow-up diabetologic more frequent than that (quarterly) envisaged by the study
* Patients requiring a transitory passage to insulin;
* Patients needing a hospitalization for the adaptation of insulin doses;
* Patients presenting a cardiologic event
* Patients presenting a hemoglobinopathy interfering with the proportioning of HbA1c;
* Patients suffering from drug-addiction, alcoholism or psychological troubles
* Type 1 or secondary diabetes
* Patients who don't need strict metabolic objectives;
* Pregnant or parturient patients
* person with no freedom.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Novo Nordisk A/S

INDUSTRY

Sponsor Role collaborator

Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Guillaume CHARPENTIER, MD

Role: STUDY_CHAIR

Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète

Pierre Yves BENHAMOU, MD PHD

Role: STUDY_CHAIR

University Hospital, Grenoble

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

CH Aix en Provence

Aix-en-Provence, , France

Site Status

Centre Hospitalier Intercommunal Alençon-Mamers

Alençon, , France

Site Status

CH Avignon

Avignon, , France

Site Status

Centre Hospitalier de Belfort Montbéliard

Belfort, , France

Site Status

CHU Jean Minjoz

Besançon, , France

Site Status

CHU de Caen

Caen, , France

Site Status

Hôpital Gabriel Montpied

Clermont-Ferrand, , France

Site Status

CH sud francilien

Corbeil-Essonnes, , France

Site Status

CH de Dreux

Dreux, , France

Site Status

CHU Pierre Zobda-Quitman

Fort de France, , France

Site Status

University Hospital Grenoble

Grenoble, , France

Site Status

CH La Rochelle

La Rochelle, , France

Site Status

CHU de Bicêtre

Le Kremlin-Bicêtre, , France

Site Status

CHU Marseille-Hôpital Nord

Marseille, , France

Site Status

CHU Marseille Hôpitaux Sud

Marseille, , France

Site Status

CH de l'Agglomération Montargoise

Montagis, , France

Site Status

CHU Hôpital Jeanne d'Arc

Nancy, , France

Site Status

CH Nanterre

Nanterre, , France

Site Status

CHU Nantes

Nantes, , France

Site Status

CHU de Nimes

Nîmes, , France

Site Status

Hopital COCHIN

Paris, , France

Site Status

Hopital Haut Leveque

Pessac, , France

Site Status

CHU de Poitiers

Poitiers, , France

Site Status

CHU Rennes

Rennes, , France

Site Status

CHU de Saint Etienne

Saint-Etienne, , France

Site Status

Hôpital Bégin

Saint-Mandé, , France

Site Status

Centre Hospitalier Strasbourg

Strasbourg, , France

Site Status

Ch Valenciennes

Valenciennes, , France

Site Status

Countries

Review the countries where the study has at least one active or historical site.

France

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2008-A00270-55

Identifier Type: -

Identifier Source: org_study_id