Human Papilloma Virus (HPV) Vaccination Among Rural African American Primary Caregivers and Daughters

NCT ID: NCT00937287

Last Updated: 2013-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

410 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-07-31

Study Completion Date

2012-07-31

Brief Summary

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African American women living in the rural South are twice as likely as Caucasian women to develop cervical cancer and die of invasive cervical cancer at a higher rate than any other racial/ethnic group in the US (1). Reasons for low HPV vaccination rates among rural African Americans are not well understood. HPV vaccination compliance is likely influenced by barriers to health care access, misinformation regarding vaccinations, religious beliefs related to sexual health and behaviors, and mistrust of the medical community (2, 3). Because the vaccination of minors requires primary caregiver consent, vaccination commitment and compliance is strongly influenced by family beliefs and communication regarding health and sexuality. To date, little research has examined the cultural, familial, and intrapersonal influences on HPV vaccination compliance among rural African American women. This study will address these gaps in the literature and provide data needed to develop effective interventions and health promotion materials to encourage HPV vaccination among rural African American women.

From a pool of approximately 800 families who are participating in ongoing longitudinal research through the Center for Family Research at the University of Georgia, the investigators will recruit 200 rural female African American youth aged 13-17 who have not received the HPV vaccine and their primary caregivers (n=200) into an observational, prospective study on vaccination commitment and compliance. The investigators hypotheses are as follows:

1. Sociocultural factors that rural African Americans experience, including discrimination, previous health care experience, religious beliefs, and community norms regarding HPV vaccination and adolescent sexual behavior, will forecast primary caregivers' HPV vaccination commitment and compliance for their daughters. The investigators also predict that primary caregivers' HPV-related knowledge and attitudes will mediate this association.
2. Sociocultural factors will influence sexual health-related family communication and interaction, primary caregivers' and youths' HPV-related attitudes, and HPV vaccination commitment and compliance.
3. Primary caregivers' attitudes, youths' attitudes, and family health communication will contribute to youths' and caregivers' vaccination commitment and compliance.
4. Youths' sexual behavior will influence their attitudes, family health communication, and vaccination commitment and compliance.

Detailed Description

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Conditions

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Human Papillomavirus

Keywords

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HPV African American Rural

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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youth and caregivers

There is no intervention in this study.

Intervention Type OTHER

No intervention is provided in this study as it is exploratory.

Interventions

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There is no intervention in this study.

No intervention is provided in this study as it is exploratory.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Rural African American girls aged 13-17
* Female parent or primary caregiver of participating daughter

Exclusion Criteria

* Girls can not be younger than age 13, or older than 17
* The target's female parent or primary caregiver must also live in the same household and agree to participate
Minimum Eligible Age

13 Years

Maximum Eligible Age

17 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Georgia

OTHER

Sponsor Role lead

Responsible Party

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Steve Kogan

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Stephanie R. Burwell, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Georgia

Locations

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The Center for Family Research

Athens, Georgia, United States

Site Status

Countries

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United States

References

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Saraiya M, Ahmed F, Krishnan S, Richards TB, Unger ER, Lawson HW. Cervical cancer incidence in a prevaccine era in the United States, 1998-2002. Obstet Gynecol. 2007 Feb;109(2 Pt 1):360-70. doi: 10.1097/01.AOG.0000254165.92653.e8.

Reference Type BACKGROUND
PMID: 17267837 (View on PubMed)

Brewer NT, Fazekas KI. Predictors of HPV vaccine acceptability: a theory-informed, systematic review. Prev Med. 2007 Aug-Sep;45(2-3):107-14. doi: 10.1016/j.ypmed.2007.05.013. Epub 2007 Jun 2.

Reference Type BACKGROUND
PMID: 17628649 (View on PubMed)

Cates JR, Brewer NT, Fazekas KI, Mitchell CE, Smith JS. Racial differences in HPV knowledge, HPV vaccine acceptability, and related beliefs among rural, southern women. J Rural Health. 2009 Winter;25(1):93-7. doi: 10.1111/j.1748-0361.2009.00204.x.

Reference Type BACKGROUND
PMID: 19166567 (View on PubMed)

Other Identifiers

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MISP 36701

Identifier Type: -

Identifier Source: org_study_id