Analysis of Expression of Specific Markers and Their Prognostic Significance in Hepatocellular Carcinoma

NCT ID: NCT00911196

Last Updated: 2017-05-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-11-30

Study Completion Date

2009-03-31

Brief Summary

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Hepatocellular carcinoma is an aggressive disease with limited therapeutic options. Therefore, new approaches to treat this type of cancer are needed with immunotherapy potentially being one of these. As a first step in the development of novel therapies, expression analysis of specific markers, including tumor antigens will be carried out, and the correlation of expression with disease variables and clinical outcome will be assessed. This will be done retrospectively using archived hepatocellular carcinoma tissue samples.

Detailed Description

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Conditions

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Hepatocellular Carcinoma

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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Group A

Retrospective analysis of already archived samples

Intervention Type OTHER

Analysis using RNA extracted from tissue samples already archived; Analysis by Fluorescent in situ hybridization (FISH) using tissue samples already archived.

Interventions

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Retrospective analysis of already archived samples

Analysis using RNA extracted from tissue samples already archived; Analysis by Fluorescent in situ hybridization (FISH) using tissue samples already archived.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* The patient has pathologically proven hepatocellular carcinoma (any stage)
* All the data required are available from patient's records

Exclusion Criteria

N/A
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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GlaxoSmithKline

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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GSK Clinical Trials

Role: STUDY_DIRECTOR

GlaxoSmithKline

Locations

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GSK Investigational Site

Taipei, , Taiwan

Site Status

GSK Investigational Site

Bangkok, , Thailand

Site Status

GSK Investigational Site

Chiang Mai, , Thailand

Site Status

Countries

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Taiwan Thailand

Other Identifiers

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111726

Identifier Type: -

Identifier Source: org_study_id

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