The Effects of Arixtra on Wound Drainage Following Total Joint Arthroplasty

NCT ID: NCT00909064

Last Updated: 2017-05-15

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

114 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-06-30

Study Completion Date

2009-12-31

Brief Summary

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The investigators hypothesize that Arixtra patients will be less likely to experience wound infection than patients who have received low-molecular weight heparin, coumadin or aspirin with mechanical compression.

Detailed Description

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Conditions

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Total Knee Replacement

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Arixtra

Effect of Arixtra on would drainage and length of stay for the patients with hip and knee replacement

Group Type EXPERIMENTAL

Fondaparinux Sodium (Arixtra)

Intervention Type DRUG

2.5 mg once per day to begin 6-8 hours after surgery and continued for 10 days.

Interventions

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Fondaparinux Sodium (Arixtra)

2.5 mg once per day to begin 6-8 hours after surgery and continued for 10 days.

Intervention Type DRUG

Other Intervention Names

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Arixtra

Eligibility Criteria

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Inclusion Criteria

* All primary unilateral TKA and THA cases will be included.

Exclusion Criteria

* Patients less than 50 kg, Patients with CrCl\<30ml/min. Revision and bilateral procedures will be excluded.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Paul Di Cesare,MD

OTHER

Sponsor Role lead

Responsible Party

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Paul Di Cesare,MD

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Paul E. DiCesare, MD

Role: PRINCIPAL_INVESTIGATOR

University of California, Davis Health System

Locations

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U C Davis

Sacramento, California, United States

Site Status

Countries

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United States

Other Identifiers

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GSK576428

Identifier Type: -

Identifier Source: secondary_id

200816251

Identifier Type: -

Identifier Source: org_study_id

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