Predictors of Cord Blood Immunoglobin E (IgE) Levels

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Background: Increased total serum IgE levels are a common characteristic of atopic diseases. Increased cord blood IgE levels, in conjunction with a family history of atopy, are associated with the development of allergic diseases in children. However, little is known about predictors of cord blood IgE levels.

Objective: The aim of our study was to identify predictors of cord blood IgE levels in an ongoing large birth cohort of infants with or without a family history of atopy.

Methods: Blood sampling of mothers was performed just before the delivery of newborns. Cord blood was also collected when the child was born. Maternal and cord blood was measured for IgE levels and cytokines. Questionnaires were administered after birth of the infant.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Thoracic Aortic Dilatation Syndromes

NCT02111668

Thoracic Aorta Dilatation Marfan Syndrome

COMPLETED

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

NCT02432079

Heterotaxy Syndrome Congenital Heart Defects

RECRUITING

Dyskinesia, Heterotaxy and Congenital Heart Disease

NCT00608556

Ciliary Dyskinesia, Primary Kartagener Syndrome Congenital Heart Defects +1 more

COMPLETED

Neuroendocrine Dysfunction in Critically Ill Pediatric Patients

NCT00207896

Critical Illness

COMPLETED

Liothyronine in Children With Single Ventricle Congenital Cardiac Malformations Undergoing the Fontan Procedure

NCT00004828

Tricuspid Atresia Heart Defects, Congenital

COMPLETED PHASE1

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Atopy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Prenatal factors

Prenatal factors to predict cord blood IgE

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Mothers in pregnancy 18 years of age or older, AND
* Mothers able to speak Chinese.

Exclusion Criteria

* Infant delivered at less than 36 weeks' gestation,
* Infant with Apgar score in 5 minutes after birth \< 7,
* Infant with a major congenital anomaly, OR
* Infant admitted to an intensive care unit.

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes