Effect of Myoma Removal on Blood Pressure and Erythropoetin Level

NCT ID: NCT00898170

Last Updated: 2009-05-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-05-31

Study Completion Date

2009-03-31

Brief Summary

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The effect of myoma removal was studied on 28 patients with hypertension and myoma by holter monitoring and erythropoetin level check.

Detailed Description

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Background:

Myoma is the most common gynecoid tumor and produces many vasoactive substances, which may be a cause for secondary hypertension. Early reports suggested the association of myoma and hypertension. We studied the effect of myoma removal on hypertension and erythropoietin level to evaluate this hypothesis.

Patients \& Methods:

In this single centered prospective cohort study, in twenty eight patients who were candidates for myomectomy due to myoma, 24 hour holter monitoring of blood pressure and serum erythropoietin were checked before and 6 weeks after hysterectomy.

Conditions

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Myoma Hypertension

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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myoma, with or without hypertension

those with myoma with or without hypertension in holter monitoring

Group Type EXPERIMENTAL

myoma removal

Intervention Type PROCEDURE

surgical removal of myoma by hysterectomy

Interventions

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myoma removal

surgical removal of myoma by hysterectomy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* candidate for myoma removal by hysterectomy
* operable
* hysterectomy is indicated

Exclusion Criteria

* patient refusal
* inoperable patients
* other secondary cases of hypertension
Minimum Eligible Age

22 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Shiraz University of Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

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shiraz university of medical sciences

Principal Investigators

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javad kojuri, M.D.

Role: PRINCIPAL_INVESTIGATOR

Shiraz University of Medical Sciences

Locations

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Cardiology Ward Shiraz University of Medical Sciences

Shiraz, Fars, Iran

Site Status

Countries

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Iran

Other Identifiers

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88-2505

Identifier Type: -

Identifier Source: org_study_id

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