Renal Magnetic Resonance (MR) Elastography in Healthy Volunteers

NCT ID: NCT00876629

Last Updated: 2019-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-03-31

Study Completion Date

2009-07-31

Brief Summary

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MR Elastography is a new technique aimed at non-invasively measuring the stiffness of tissues. It has recently given interesting results in the assessment of liver fibrosis.

The objectives of the current study are:

1. to develop an imaging protocol for MR Elastography of the kidneys;
2. To calculate the stiffness of normal kidneys;
3. To evaluate the variability of the measurements of kidney stiffness by repeating the procedure twice on the same volunteers.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Interventions

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Pneumatic Driver

Ten healthy volunteers will undergo MR Elastography using a pneumatic driver connected to a commercially available speaker and the stiffness of the left kidney will be measured.

The examination will be repeated on the same volunteers at least one month later and the same stiffness measurements will be performed.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 40
* Signed informed consent form
* Insured by the French Social Security

Exclusion Criteria

* Pregnancy
* Personal or familial history of kidney disease
* Hypertension
* Diabetes
* Contraindication to MRI
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Hôpital E. Herriot

Principal Investigators

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Olivier Rouvière, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpital E. Herriot

Locations

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Department of Urinary an Vascular Radiology, Hôpital E. Herriot

Lyon, , France

Site Status

Countries

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France

References

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Rouviere O, Souchon R, Pagnoux G, Menager JM, Chapelon JY. Magnetic resonance elastography of the kidneys: feasibility and reproducibility in young healthy adults. J Magn Reson Imaging. 2011 Oct;34(4):880-6. doi: 10.1002/jmri.22670. Epub 2011 Jul 18.

Reference Type RESULT
PMID: 21769970 (View on PubMed)

Other Identifiers

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2008.529

Identifier Type: -

Identifier Source: org_study_id

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