Prognosis and Survival Estimates in Palliative Therapy

NCT ID: NCT00871520

Last Updated: 2016-08-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

612 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-04-30

Study Completion Date

2016-08-31

Brief Summary

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The accuracy of clinical survival estimates is tested in comparison to objective prognostic scores.

Detailed Description

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* At presentation a clinical survival estimate is obtained in each patient.
* Survival is also estimated using published prognostic scores in palliative care.
* Prognostic scores based on blood samples, general symptoms, complaints, and performance status are calculated and validated, respectively
* Each patient completes questionnaires on psychological distress
* Survival estimates are limited to 6 months.
* Each patient is followed for at least 6 months.

Conditions

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Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Palliative Therapy

Patients referred to the oncology / radiation oncology departments for palliative therapy.

no specific interventions

Intervention Type OTHER

There are no specific interventions in this observational study

Interventions

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no specific interventions

There are no specific interventions in this observational study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* oncologic disease confirmed
* incurable locally advanced or metastatic disease
* palliative treatment intended
* age \> 18
* able to understand the study protocol
* able to complete the forms with assistance if necessary

Exclusion Criteria

* therapy with curative intent
* regular clinical follow-up visit without disease progression
* ongoing therapy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Heinrich-Heine University, Duesseldorf

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Stephan Gripp, Dr.

Role: PRINCIPAL_INVESTIGATOR

Universtity Hospital Duesseldorf, Radiation Oncology Department

Locations

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University Hospital Duesseldorf, Radiation Oncology Dept.

Düsseldorf, North Rhine-Westphalia, Germany

Site Status

Sana Kliniken Duesseldorf Benrath

Düsseldorf, North Rhine-Westphalia, Germany

Site Status

Sana Kliniken Duesseldorf Gerresheim, MVZ Onkologie

Düsseldorf, North Rhine-Westphalia, Germany

Site Status

Countries

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Germany

References

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Gripp S, Moeller S, Bolke E, Schmitt G, Matuschek C, Asgari S, Asgharzadeh F, Roth S, Budach W, Franz M, Willers R. Survival prediction in terminally ill cancer patients by clinical estimates, laboratory tests, and self-rated anxiety and depression. J Clin Oncol. 2007 Aug 1;25(22):3313-20. doi: 10.1200/JCO.2006.10.5411.

Reference Type BACKGROUND
PMID: 17664480 (View on PubMed)

Other Identifiers

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Pro-08

Identifier Type: -

Identifier Source: org_study_id

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