Two Dimensional (2D) Silicon Transducer-Compression Plates for Breast Ultrasound

NCT ID: NCT00859261

Last Updated: 2016-05-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-03-31

Study Completion Date

2015-02-28

Brief Summary

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The study purpose is to help in the developement of 3 dimensional breast ultrasound imaging.

Detailed Description

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To assist in the developement of 3 dimensional breast ultrasound imaging and when possible compare the ultrasound results with 3D mammography (digital tomosynthesis mammography)or clinical mammography and ultrasound. Hopefully that this new, 3D ultrasound imaging can provide important information not found on mammograms or routine breast ultrasound.

Conditions

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Breast Tumor Breast Cysts

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Breast imaging using Ultrasound and Photoacoustic

Evaluating 3D ultrasound for breast abnormalities/masses/cysts. This includes ultrasound imaging and possibly photoacoustic imaging.

Group Type EXPERIMENTAL

Experimental 3D Breast Ultrasound imaging

Intervention Type PROCEDURE

Subjects will be seated and have the indicated breast positioned in the 3D breast ultrasound imaging device. An ultrasound gel will be applied to the breast by the technician. The breast will be gently compressed between the ultrasound plates to facilitate the 3D (dimensional)breast imaging. This imaging session will take approximately 30 minutes to complete.

Experimental Photoacoustic Imaging

Intervention Type PROCEDURE

Subjects will be placed in a seated position for the photoacoustic tomography(PAT) imaging. The subjects will be given a laser protective mask to wear. Each subject will be instructed how to wear this mask(goggles) to protect their eyes during the imaging session. Pulse monitor leads may be placed on their chest to allow the computer to record the images of blood flow in the breast. The breast will be placed on the laser device platform and positioned so that the laser beam is appropriately directed to the targeted area of the breast. During the imaging the temperature of the skin under laser light, will be checked often with a thermometer to make sure that the skin is not getting too hot. This laser based imaging scan will take approximately 10 minutes to complete.

Interventions

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Experimental 3D Breast Ultrasound imaging

Subjects will be seated and have the indicated breast positioned in the 3D breast ultrasound imaging device. An ultrasound gel will be applied to the breast by the technician. The breast will be gently compressed between the ultrasound plates to facilitate the 3D (dimensional)breast imaging. This imaging session will take approximately 30 minutes to complete.

Intervention Type PROCEDURE

Experimental Photoacoustic Imaging

Subjects will be placed in a seated position for the photoacoustic tomography(PAT) imaging. The subjects will be given a laser protective mask to wear. Each subject will be instructed how to wear this mask(goggles) to protect their eyes during the imaging session. Pulse monitor leads may be placed on their chest to allow the computer to record the images of blood flow in the breast. The breast will be placed on the laser device platform and positioned so that the laser beam is appropriately directed to the targeted area of the breast. During the imaging the temperature of the skin under laser light, will be checked often with a thermometer to make sure that the skin is not getting too hot. This laser based imaging scan will take approximately 10 minutes to complete.

Intervention Type PROCEDURE

Other Intervention Names

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Photoacoustic Tomography (PAT)

Eligibility Criteria

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Inclusion Criteria

* Healthy women OR
* Women with suspected benign masses who may/or may not be going to biopsy
* Women with cysts where no biopsy is recommended

Exclusion Criteria

* Women who are pregnant
* Women with breast implants
* Prisoners
Minimum Eligible Age

30 Years

Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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National Institutes of Health (NIH)

NIH

Sponsor Role collaborator

National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

University of Michigan

OTHER

Sponsor Role lead

Responsible Party

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Paul L. Carson Ph.D

Principal Investigator ( Ph.D )

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Paul Carson, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Michigan Basic Science Division

Locations

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University of Michigan

Ann Arbor, Michigan, United States

Site Status

Countries

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United States

Other Identifiers

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2R01CA091713

Identifier Type: NIH

Identifier Source: secondary_id

View Link

R01CA115267

Identifier Type: NIH

Identifier Source: secondary_id

View Link

HUM 15464

Identifier Type: -

Identifier Source: org_study_id

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