L-asparaginase Monotherapy as Salvage Treatment in Patients With NK/T Cell Lymphoma
NCT ID: NCT00854425
Last Updated: 2012-02-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
40 participants
INTERVENTIONAL
2008-06-30
2012-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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L-asp
L-asparaginase
L-asparaginase 600mg/m2 days 1-7 repeated every 3 weeks for a total of 6 cycles
Interventions
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L-asparaginase
L-asparaginase 600mg/m2 days 1-7 repeated every 3 weeks for a total of 6 cycles
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Histological confirmed NK/T cell lymphoma with progressive or recurrent disease
* ECOG performance status 0-2
* Life expectancy of more than 3 months
* Normal laboratory values: hemoglobin \> 80 g/dl, neutrophil \> 2×109/L, platelet \> 100×109/L, serum creatine \< 1.5×upper limitation of normal (ULN), serum bilirubin \< 1.5×ULN, ALT and AST \< 2.5×ULN
Exclusion Criteria
* Serious uncontrolled diseases and intercurrent infection
* The evidence of CNS metastasis
* History of other malignancies except cured basal cell carcinoma of skin and carcinoma in-situ of uterine cervix
18 Years
75 Years
ALL
No
Sponsors
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Fudan University
OTHER
Responsible Party
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Ye Guo
Dr.
Principal Investigators
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Ye Guo, MD
Role: PRINCIPAL_INVESTIGATOR
Fudan University
Locations
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Fudan University Cancer Hospital
Shanghai, Shanghai Municipality, China
Countries
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Other Identifiers
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L-asp-NK/T
Identifier Type: -
Identifier Source: org_study_id
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