Pro-inflammatory Cytokines in Blood From Orthopedic Surgery Compared to Abdominal Aneurysm Repair
NCT ID: NCT00851149
Last Updated: 2010-06-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
20 participants
OBSERVATIONAL
2009-11-30
2010-05-31
Brief Summary
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Detailed Description
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Primary outcome:
Pro-inflammatory cytokines (IL-6, IL-8 and TNF-α) and complement activation (C3a) in blood samples collected from surgery field. Comparison between the 2 groups.
Secondary outcome:
Haemoglobin, Trc, INR in blood samples and plasma will be analysed and compared between the 2 groups.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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1/10
Abdominal aortic surgery patients
Sangvia blood sampling system
Blood collected from abdominal aortic repair patients are compared against blood collected from total hip replacement patients
2/10
Total hip replacement patients
Sangvia blood sampling system
Blood collected from abdominal aortic repair patients are compared against blood collected from total hip replacement patients
Interventions
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Sangvia blood sampling system
Blood collected from abdominal aortic repair patients are compared against blood collected from total hip replacement patients
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients under 18 years
* Patients who are included in pharmaceutical studies
* Opioids-, benzodiazepines-, antiepileptic drugs-, alcohol- and α2-agonists abuse
* Pregnant and breastfeeding women
* Patients with known hypersensitivity for opioids, propofol or volatile anesthetics
* Patients with serious arrhythmias (atrial fibrillation/flutter is acceptable)
* Uncontrolled hypertension, serious psychiatric disease
* Patients with unstable angina pectoris or myocardial infarction the last month before inclusion
* Acute abdominal aortic surgery (acute dissection or rupture)
* Planned laparoscopic abdominal aortic aneurysm surgery
* Transfusion of blood products last month before surgery
* Glucocorticoid users
18 Years
ALL
No
Sponsors
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Oslo University Hospital
OTHER
Dentsply Sirona Implants and Consumables
INDUSTRY
Sykehuset i Vestfold HF
OTHER
Responsible Party
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Hospital in Vestfold HF
Principal Investigators
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Espen Lindholm, Md
Role: PRINCIPAL_INVESTIGATOR
Sykehuset i Vestfold HF
Locations
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Sykehuset i Vestfold HF
Tønsberg, , Norway
Countries
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Other Identifiers
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6.2009.36
Identifier Type: -
Identifier Source: org_study_id
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