Stevens-Johnson Syndrome Antimicrobial

NCT ID: NCT00844038

Last Updated: 2009-02-13

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 1 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2008-08-31
• Study Completion Date: 2008-12-31

Brief Summary

Steven-Johnson's syndrome, or great multiform erythema, appears as a systemic disturbance, with skin involvement and mucous membranes, related to several factors, such as, viral or bacterial infections and mainly the administration of medicines, in general painkillers and antibiotics. The objective of this work is report the emergence of ulcerative vesicle -bubble chronic disease in areas of lips, gum, tongue and genital mucous membrane in a 26 year-old patient, leucoderma and masculine gender, in treatment of breathing infection with sulfametoxazol-trimetropima, having been diagnosed as syndrome of Steven-Johnson.

Detailed Description

Among the serious medicaments reactions, there are as great representative the Mucocutaneous Disorders immunological mediated. Steven-Johnson's syndrome, or great multiform erythema, appears as a systemic disturbance, with skin involvement and mucous membranes, related to several factors, such as, viral or bacterial infections and mainly the administration of medicines, in general painkillers and antibiotics. The objective of this work is report the emergence of ulcerative vesicle -bubble chronic disease in areas of lips, gum, tongue and genital mucous membrane in a 26 year-old patient, leucoderma and masculine gender, in treatment of breathing infection with sulfametoxazol-trimetropima, having been diagnosed as syndrome of Steven-Johnson.

Conditions

Stevens-Johnson Syndrome

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Study Groups

1

Sick

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Stevens-Johnson syndrome associated with antimicrobial

Exclusion Criteria

• Not sick

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: No

Sponsors

University of Pernambuco

OTHER

Sponsor Role: lead

Responsible Party

University of Pernambuco

Principal Investigators

Edwaldo Dr Dourado, Doctor

Role: PRINCIPAL_INVESTIGATOR

University of Pernambuco

Locations

University of Pernambuco

Recife, Pernambuco, Brazil

Countries

Brazil

References

Vanfleteren I, Van Gysel D, De Brandt C. Stevens-Johnson syndrome: a diagnostic challenge in the absence of skin lesions. Pediatr Dermatol. 2003 Jan-Feb;20(1):52-6. doi: 10.1046/j.1525-1470.2003.03012.x.

Reference Type: RESULT

PMID: 12558848 (View on PubMed)

Other Identifiers

558187121279

Identifier Type: -

Identifier Source: secondary_id

SSJ1

Identifier Type: -

Identifier Source: org_study_id