Motion Correction of Positron Emission Tomography (PET) Data Using Amplitude Gating

NCT ID: NCT00843219

Last Updated: 2016-02-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

12 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-03-31

Study Completion Date

2011-12-31

Brief Summary

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Objectives:

Evaluation of an amplitude based gated Positron Emission Tomography (PET) data acquisition system for all GE Discovery Positron Emission Tomography/ Computed Tomography (PET/CT) scanners.

Detailed Description

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Routine PET/CT scans are taken while patients are breathing normally. The motions made by breathing can reduce the image quality of the scan. Minimizing the effects of this motion by taking the images and processing the scans differently may improve the image quality.

The PET/CT Scan:

If you agree to take part in this study, an elastic belt will be placed around your lower chest/upper abdomen before your routine PET/CT scan. This belt is used to track your breathing motion. This information will be used to help process the scan.

Your PET/CT scan will be performed as usual. During the scan, researchers will focus on your lower chest/upper abdomen (areas that experience breathing motion). Having to focus on this area might extend the scan by up to 10 minutes.

The additional scan time will not increase your radiation exposure since only PET scanning will be performed.

Length of Study:

Your participation on this study will be complete when your scheduled PET/CT scan is complete.

This is an investigational study. The imaging focused on your lower chest/upper abdomen during the scan is investigational.

Up to 26 patients will take part in this study. All will be enrolled at M. D. Anderson.

Conditions

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Lung Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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PET/CT Scan

PET/CT Scan

Intervention Type PROCEDURE

PET/CT scan performed with elastic belt around lower chest/upper abdomen to track breathing motion.

Interventions

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PET/CT Scan

PET/CT scan performed with elastic belt around lower chest/upper abdomen to track breathing motion.

Intervention Type PROCEDURE

Other Intervention Names

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Positron Emission Tomography Positron Emission Tomography/Computed Tomography Computed Tomography

Eligibility Criteria

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Inclusion Criteria

1. Patients with lung or liver lesions measuring 0.5-2cm in diameter will be considered.
2. Patients that are scheduled to be imaged in the PET/CT suite at the Mays Building will only be considered.

Exclusion Criteria

1. Pediatric patients (younger than 18 years) will be excluded.
2. Patients that cannot tolerate being scanned for an additional 10 minutes with arms above their head will be excluded.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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GE Healthcare

INDUSTRY

Sponsor Role collaborator

M.D. Anderson Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Osama R Mawlawi, PHD

Role: PRINCIPAL_INVESTIGATOR

UT MD Anderson Cancer Center

Locations

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UT MD Anderson Cancer Center

Houston, Texas, United States

Site Status

Countries

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United States

Related Links

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http://www.mdanderson.org

UT MD Anderson Cancer Center

Other Identifiers

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2008-0851

Identifier Type: -

Identifier Source: org_study_id

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