The Idiopathic Scoliosis and Its Treatment (Orthopaedic and Surgery): Effect of the Severity, the Orthosis and the Arthrodesis on the Gait
NCT ID: NCT00842218
Last Updated: 2009-02-12
Study Results
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Basic Information
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UNKNOWN
50 participants
OBSERVATIONAL
2009-01-31
2009-09-30
Brief Summary
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Detailed Description
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We hypothesize first that, the spinal deformations in AIS, producing a stiffness of the trunk, pelvic and hip motions, will deteriorate the gait by reducing the segmental mobilities, increasing the mechanical work and the energy cost and second that the severity of the frontal curves will be more damaging on this parameters. To this end, we hope to gain valuable insight as to the functional effects of the scoliosis aggravation from a more dynamic perspective.
Material Fifty-four female adolescents will be included in the study. This sample consists in two groups: healthy girls and girls with adolescent idiopathic scoliosis (divided in 3 subgroups according to the Cobb angle range) \[9\].
A standard full spine XRay assessment will be performed to measure the Cobb angle curve, the frontal body balance, the apical vertebral rotation \[13\].
Gait will be assessed by a three-dimensional analysis, including synchronous kinematic \[4\], electromyographic (EMG) \[14\], mechanic \[5, 6, 15\] and energetic measurements \[1, 2, 12\].
The sessions begins with a rest period, in which the subjects stand barefoot on the motor driven treadmill for the static calibration of kinematic and energetic variables. Thereafter, the subjects will be asked to walk at a constant speed of 4 km h-1 for a few minutes until a steady state will be reached and maintained for at least two minutes. Then, energetic variables will be computed for two minutes. Other variables will simultaneously be recorded for twenty seconds and averaged for ten successive strides. The mean of each value will be used for statistical analysis. Scoliosis patients will be assessed at T0 i.e. before any treatment and at T1 i.e. one year after the starting of the orthosis wearing (scoliosis subgroup 2) or the surgery (scoliosis subgroup 3)
Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Scoliosis subjects : scoliosis diagnosed by X-Ray assessment
Exclusion Criteria
12 Years
18 Years
FEMALE
Yes
Sponsors
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Cliniques universitaires Saint-Luc- Université Catholique de Louvain
OTHER
Responsible Party
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Orthopaedic Research Laboratory , Université catholique de Louvain, Brussels, Belgium
Principal Investigators
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Mahaudens Philippe, Mr
Role: PRINCIPAL_INVESTIGATOR
Université Catholique de Louvain
Locations
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Université Catholique de Louvain - Cliniques universitaires Saint-Luc
Brussels, , Belgium
Countries
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Central Contacts
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Facility Contacts
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References
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Cavagna GA, Franzetti P, Fuchimoto T. The mechanics of walking in children. J Physiol. 1983 Oct;343:323-39. doi: 10.1113/jphysiol.1983.sp014895.
Cavagna GA, Kaneko M. Mechanical work and efficiency in level walking and running. J Physiol. 1977 Jun;268(2):467--81. doi: 10.1113/jphysiol.1977.sp011866.
Danielsson AJ, Romberg K, Nachemson AL. Spinal range of motion, muscle endurance, and back pain and function at least 20 years after fusion or brace treatment for adolescent idiopathic scoliosis: a case-control study. Spine (Phila Pa 1976). 2006 Feb 1;31(3):275-83. doi: 10.1097/01.brs.0000197652.52890.71.
Davis RB OS, Tyburski D, Gage JR (1991) A gait analysis data collection and reduction technique. Hum Mov Sci 10:575-587
Detrembleur C, van den Hecke A, Dierick F. Motion of the body centre of gravity as a summary indicator of the mechanics of human pathological gait. Gait Posture. 2000 Dec;12(3):243-50. doi: 10.1016/s0966-6362(00)00081-3.
Detrembleur C, Vanmarsenille JM, De Cuyper F, Dierick F. Relationship between energy cost, gait speed, vertical displacement of centre of body mass and efficiency of pendulum-like mechanism in unilateral amputee gait. Gait Posture. 2005 Apr;21(3):333-40. doi: 10.1016/j.gaitpost.2004.04.005.
Karski T. Biomechanical factors in the etiology of idiopathic scoliosis: two etiopathological groups of spinal deformities. Ortop Traumatol Rehabil. 2004 Nov-Dec;6(6):800-8.
Kramers-de Quervain IA, Muller R, Stacoff A, Grob D, Stussi E. Gait analysis in patients with idiopathic scoliosis. Eur Spine J. 2004 Aug;13(5):449-56. doi: 10.1007/s00586-003-0588-x. Epub 2004 Apr 3.
Lenke LG, Betz RR, Harms J, Bridwell KH, Clements DH, Lowe TG, Blanke K. Adolescent idiopathic scoliosis: a new classification to determine extent of spinal arthrodesis. J Bone Joint Surg Am. 2001 Aug;83(8):1169-81.
Leong JC, Lu WW, Luk KD, Karlberg EM. Kinematics of the chest cage and spine during breathing in healthy individuals and in patients with adolescent idiopathic scoliosis. Spine (Phila Pa 1976). 1999 Jul 1;24(13):1310-5. doi: 10.1097/00007632-199907010-00007.
Mahaudens P, Thonnard JL, Detrembleur C. Influence of structural pelvic disorders during standing and walking in adolescents with idiopathic scoliosis. Spine J. 2005 Jul-Aug;5(4):427-33. doi: 10.1016/j.spinee.2004.11.014.
McArdle W, Katch F, Katch V (1996) Exercise physiology: Energy, Nutrition, and Human Performance. Baltimore
Roche AF, Eyman SL, Davila GH. Skeletal age prediction. J Pediatr. 1971 Jun;78(6):997-1003. doi: 10.1016/s0022-3476(71)80430-4. No abstract available.
Van Boxtel GJ, Geraats LH, Van den Berg-Lenssen MM, Brunia CH. Detection of EMG onset in ERP research. Psychophysiology. 1993 Jul;30(4):405-12. doi: 10.1111/j.1469-8986.1993.tb02062.x.
Willems PA, Cavagna GA, Heglund NC. External, internal and total work in human locomotion. J Exp Biol. 1995 Feb;198(Pt 2):379-93. doi: 10.1242/jeb.198.2.379.
Other Identifiers
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READ-Mahaudens-01
Identifier Type: -
Identifier Source: org_study_id
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