Urinary Incontinence: Reproductive/Hormonal Risk Factors

NCT ID: NCT00836979

Last Updated: 2015-04-07

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 2161 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2008-10-31
• Study Completion Date: 2012-12-31

Brief Summary

This study is a continuation or follow-up of two previous studies (RRISK and RRISK2) conducted at the Kaiser Division of Research. This study will invite previous study participants, as well as a randomly selected group of Northern California Kaiser Permanente Members, to participate in an interview, mailed survey and lab visit. The purpose of this study is to examine the risk factors for bladder and pelvic problems.

Detailed Description

Using a cohort established during two previous studies (RRISK, CN-97Svand-01-H and RRISK2 CN-02Svand-07-H), this study will follow a well characterized cohort of middle-aged and older women who have been members of Kaiser Permanente Medical Care Plan (KPMCP) of Northern California continuously since age 18. The cohort is composed of over 2000 women for whom we have data from abstracted medical records, in-person interview, voiding diaries, physical assessments, laboratory data, and banked sera. Our cohort is unique in including a substantial number of women from the 4 major ethnic/race groups (white non-Hispanic, Black, Asian and Hispanic.) For this study, we will re-interview as many study participants from RRISK and RRISK2 as are willing. This study will also expand to further increase its diversity by adding a total of 450 Black, Asian and Hispanic women to the cohort. The overall goal of the study is to advance our understanding of mechanisms of Urinary Incontinence and facilitate the translational development of novel approaches to treatment and prevention.

Conditions

Urinary Incontinence

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

• previously participated in the RRISK or RRISK2 studies at the kaiser Division of Research.

Exclusion Criteria

• Not a part of the previous RRISK or RRISK2 cohorts.

• Minimum Eligible Age: 40 Years
• Maximum Eligible Age: 69 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

University of California, San Francisco

OTHER

Sponsor Role: collaborator

Kaiser Permanente

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Stephen K Van Den Eeden, PhD

Role: PRINCIPAL_INVESTIGATOR

Kaiser Division of Research

Jeanette Brown, MD

Role: PRINCIPAL_INVESTIGATOR

UCSF/Mr. Zion WHCRC

David Thom, MD

Role: PRINCIPAL_INVESTIGATOR

UCSF/Family and Community Medicine

Locations

Kaiser Division of Research

Oakland, California, United States

Countries

United States

Other Identifiers

P50DK064538

Identifier Type: NIH

Identifier Source: secondary_id

View Link

CN-08Svand-01-H

Identifier Type: -

Identifier Source: org_study_id