Steady State Kinetics of l-Methamphetamine and Validation of Sensitivity of Dose Estimation
NCT ID: NCT00829634
Last Updated: 2013-05-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
12 participants
INTERVENTIONAL
2008-10-31
2009-09-30
Brief Summary
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Detailed Description
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Once enrolled the study will take two weeks. During the first week subjects attend daily, hour-long outpatient visits at San Francisco General Hospital. At these visits subjects will receive an oral dose of l-methamphetamine, have their vitals read, answer questionnaires and receive a blood draw.
During the second week of the study subjects are admitted to San Francisco General Hospital for a week long inpatient stay. During this stay the subject continues to receive l-methamphetamine but also receives three doses of d-methamphetamine on three separate days. In addition the subject receives blood draws, has their urine collected, and answers questionnaires.
Conditions
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Study Design
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NA
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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l-methamphetamine
l-methamphetamine
5mg of l-methamphetamine per day throughout the 2 week study
d-methamphetamine
15mg on Study Day 9, 30mg on Study Day 11, 45mg on Study Day 13
Interventions
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l-methamphetamine
5mg of l-methamphetamine per day throughout the 2 week study
d-methamphetamine
15mg on Study Day 9, 30mg on Study Day 11, 45mg on Study Day 13
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Must have some experience with methamphetamine
18 Years
50 Years
ALL
Yes
Sponsors
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San Francisco General Hospital
OTHER
University of California, San Francisco
OTHER
National Institutes of Health (NIH)
NIH
California Pacific Medical Center Research Institute
OTHER
Responsible Party
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John Mendelson, MD
Senior Scientist
Locations
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CPMC Addiction & Pharmacology Research Laboratory (APRL)
San Francisco, California, United States
Countries
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Other Identifiers
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27.092
Identifier Type: -
Identifier Source: org_study_id
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