Alcohol Addiction and Otorhinolaryngology Cancer

NCT ID: NCT00825448

Last Updated: 2012-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

115 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-01-31

Study Completion Date

2013-01-31

Brief Summary

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The aim of the study is to compare the hospitalisation period in ORL surgery for two groups of patients. One of them will be treated for alcohol addiction to weaning them before the surgery ORL. The other group will be treated with usual methods.

Detailed Description

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Alcohol, associated or not associated with tobacco, is known to increase the incidence of ORL cancer. So, in fact many patients perform their ORL surgery operation in spite of their alcohol addiction.

Many studies showed that a post surgery weaning syndrome increases morbidity and mortality.

So our study will focuses on the benefits of pre surgery medical weaning program.

The protocol is an open randomised, prospective study. The patient will be divided in two groups. In one hand, the first group is designed as "treated" will get alcohol weaning in the hospital alcohol department. The patient will be hospitalized during one week before the ORL surgery.

During this hospitalisation, the patient will receive medicinal treatment, medical follow-up and psychological counselling.

In the other hand, the second group designed as "control group" will be hospitalized directly in ORL surgery department. The patient will be received a treatment for alcohol weaning according to their symptom.

After their hospitalisation, the treated group will be followed-up regularly for their alcohol addiction either in support group or in individual counselling. The control group will be followed-up with the usual method in the ORL surgery department.

The expected result is to improve the care for patients with alcohol addiction and who must have an ORL surgery reducing the hospitalisation duration, the level of post operative complication and increasing the abstinence level. 115 patients will be included in this study.

Conditions

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Cancer of the Upper Aero-digestive Tract Alcoholism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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2

patient in hospital a week before the date of surgery for the treatment of his addiction alcohol

Group Type EXPERIMENTAL

Hospitalization for a week

Intervention Type PROCEDURE

Patient in hospital a week before the date of surgery for the treatment of their addiction to alcohol (alcohol weaning)

1

no treatment of his addiction alcohol during a week before the date of surgery

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Hospitalization for a week

Patient in hospital a week before the date of surgery for the treatment of their addiction to alcohol (alcohol weaning)

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age 18-80 years, male or female
* Clinically and histologically verified ORL cancer required surgery
* Patient with alcohol addiction
* Men must consume 21 glasses of wine a week
* Women must consume 14 glasses of wine a week
* CPAM affiliation
* Able to give written informed consent to participate in the study

Exclusion Criteria

* Inability to give informed consent
* Patient with regulatory authority or private patient freedom
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute, France

OTHER_GOV

Sponsor Role collaborator

Department of Clinical Research and Innovation

OTHER

Sponsor Role lead

Responsible Party

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Department of Clinical Research and Innovation

Department of Clinical Research and Innovation (drc)

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Albert TRAN, PhD

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier Universitaire de Nice

Locations

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Fédération des maladies de l'appareil digestif - Hôpital ARCHET

Nice, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Eve GELSI, MD

Role: CONTACT

+33 4 92 03 60 18

Albert TRAN, PhD

Role: CONTACT

+ 33 4 92 03 62 32

Facility Contacts

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Eve Gelsi, MD

Role: primary

+ 33 4 92 03 60 18

Albert Tran, PhD

Role: backup

+ 33 4 92 03 62 32

Other Identifiers

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2008-A00634-51

Identifier Type: -

Identifier Source: org_study_id

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