Is Regular Chest Physiotherapy an Effective Treatment in Severe, Non Cystic Fibrosis Bronchiectasis?
NCT ID: NCT00816309
Last Updated: 2011-04-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
20 participants
INTERVENTIONAL
2007-10-31
2009-03-31
Brief Summary
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Detailed Description
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The study is entitled "Is regular chest physiotherapy an effective treatment in severe, non cystic fibrosis bronchiectasis?" This is a small randomised controlled pilot crossover study assessing the efficacy of regular chest physiotherapy using an Acapella mouthpiece in severe non cystic fibrosis bronchiectasis. 10 patients will be randomised to receive full instruction in use of the Acapella device (twice daily therapy) and ten patients will continue with their standard treatment regimen. The study will be conducted over seven months.
At the beginning we will randomly allocate them to receive either the current standard treatment regimen for bronchiectasis or to receive instruction in the use of the Acapella physiotherapy device for the first 3 months.
After these 3 months all will receive the current standard treatment regimen for 1 month.
Following this, those that received current standard treatment will receive Acapella physiotherapy device for 3 months and those that received Acapella physiotherapy device will stop this and receive current standard treatment for 3 months.
All participants will be reviewed on 6 occasions (start of study and then at months 1, 2, 3, 4 and 6). At each review, sputum samples will be collected, routine bloods, spirometry and exercise testing performed and health related quality of life questionnaires be completed.
At the end of the study should patients have felt benefit with the physiotherapy with the Acapella device, they should continue using it regularly on a twice-daily basis.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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Acapella Physiotherapy
Physiotherapy with acapella versus no physiotherapy
Acapella Physiotherapy
twice daily- around 20 minutes
No physiotherapy
Physiotherapy with acapella versus no physiotherapy
No interventions assigned to this group
Interventions
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Acapella Physiotherapy
twice daily- around 20 minutes
Eligibility Criteria
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Inclusion Criteria
* No regular chest physiotherapy
Exclusion Criteria
60 Years
85 Years
ALL
No
Sponsors
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NHS Lothian
OTHER_GOV
Responsible Party
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NHS Lothian
Principal Investigators
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Adam T Hill, MBChB MD
Role: PRINCIPAL_INVESTIGATOR
NHS Lothian
Locations
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Royal Infirmary of Edinburgh
Edinburgh, Scotland, United Kingdom
Countries
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References
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Murray MP, Pentland JL, Hill AT. A randomised crossover trial of chest physiotherapy in non-cystic fibrosis bronchiectasis. Eur Respir J. 2009 Nov;34(5):1086-92. doi: 10.1183/09031936.00055509. Epub 2009 Jun 18.
Other Identifiers
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AH003
Identifier Type: -
Identifier Source: org_study_id
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