Impact of Education During Pregnancy in Overweight Pregnant Women

NCT ID: NCT00804765

Last Updated: 2025-11-20

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 275 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2008-09-30
• Study Completion Date: 2013-11-30

Brief Summary

Metabolic environment of the foetus during pregnancy in obese women is altered and the child exposed at an increased risk of obesity. Rapid infancy and childhood weight gain is associated with subsequent obesity.

The purpose of the study is to test the efficacy of an educational intervention during pregnancy in obese or overweight women, on the reduction of rapid infancy weight gain in the two first years of life.

Detailed Description

In a first time, we propose to pregnant overweight women to participate a study based on the follow up of their pregnancy and of their child during the two first years of life. Women in agreement with the study sign a consent form and fill in a questionnaire about their quality of live.

We secondly randomized the women in two groups:

Group A: in this group an intervention is delivered. It provide education, at regularly scheduled sessions (20 weeks, 28 weeks, 35 weeks, and 2 month after delivering) and two dietary consulting. The sessions that stress about healthy eating and modest exercise assemble several women (no more than 10). Women in agreement with this intervention sign a consent form.

Group B: in this group, pregnant women are managed with standard care (at least one dietary consulting is proposed around 26 weeks).

Risk factors for child obesity are researched by questionnaire (parents smoking habit, mother and father level of education, family history of obesity, risk factors for gestational diabetes…). Mother weight measured at every clinic visit, is recorded as complications during pregnancy (HTA, preeclampsia, diabetes, fetal malformation …) and during delivery. Mother glycosylated haemoglobin is measured at birth.

Variables of interest for the children included at birth: gestational age, sex, neonatal pathology, hospitalisations and hypoglycaemia episode. Measurement, and method of infant feeding are recorded at birth, and by phone call every 2 months during 6 months, at 9 month, 1 year, 18 months and 2 years. At 4 months the mother fill in a questionnaire about the amount of milk or other foods eaten by the child.

A visit is planed at 2 years for:

• clinical examination of the child,
• recording of his nutritional and exercise habits
• questionnaire about quality of life of the mother and her health
• measurement of her BMI, arterial pressure, glycaemia before and after 75 g oral glucose-tolerance test, glycosylated hemoglobin, and lipid test.

Conditions

Overweight; Obesity; Pregnancy; Childhood Obesity

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

1

Therapeutic education

Group Type: EXPERIMENTAL

Therapeutic education

Intervention Type: OTHER

Intensive training individual and collective teaching

2

Group Type: PLACEBO_COMPARATOR

Follow-up

Intervention Type: OTHER

classical follow-up with two individual consultations

Interventions

Therapeutic education

Intensive training individual and collective teaching

Intervention Type: OTHER

Follow-up

classical follow-up with two individual consultations

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Pregnant women who agree the study
• BMI > 25 kg/m². BMI is based on retrospective self reported weight of the patient before pregnancy.
• No more that 21 weeks of gestation.
• Social security

Exclusion Criteria

• women younger than 18 yrs,
• multiple gestation,
• high risk pregnancy,
• psychiatric pathology,
• diabetes diagnosed before the inclusion
• fetal malformation
• history of obesity surgery
• Women with no understanding of French language
• Women planning to move to another area.

• Minimum Eligible Age: 18 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

URC-CIC Paris Descartes Necker Cochin

OTHER

Sponsor Role: collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Sophie PARAT, MD

Role: PRINCIPAL_INVESTIGATOR

Assistance Publique - Hôpitaux de Paris

Locations

Hôpital Necker

Paris, , France

Countries

France

References

Parat S, Negre V, Baptiste A, Valensi P, Bertrand AM, Chollet C, Dabbas M, Altman JJ, Lapillonne A, Treluyer JM, Elie C, Tauber M, Lorenzini F, Cosson E. Prenatal education of overweight or obese pregnant women to prevent childhood overweight (the ETOIG study): an open-label, randomized controlled trial. Int J Obes (Lond). 2019 Feb;43(2):362-373. doi: 10.1038/s41366-018-0205-z. Epub 2018 Sep 21.

Reference Type: RESULT

PMID: 30242235 (View on PubMed)

Other Identifiers

AOM07093

Identifier Type: -

Identifier Source: org_study_id