Study Results
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View full resultsBasic Information
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COMPLETED
19 participants
OBSERVATIONAL
2005-10-31
2011-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Manic Subject with DWM Hyperintensities >2
Subjects with acute mania who were treated with naturalistic protocol (starting with valproic acid) who had a BOYKO DWM Hyperintensity rating \>2 and a YMRS \<15 at week 3.
Valproic Acid
Tablets, 250mg-3000mg
Manic Subjects with DWM Hyperintensities <3
Subjects with acute mania who were treated with naturalistic protocol (starting with valproic acid)who had a BOYKO DWM Hyperintensity rating \<3 and a YMRS \<15 at week 3.
Valproic Acid
Tablets, 250mg-3000mg
Interventions
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Valproic Acid
Tablets, 250mg-3000mg
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
2. 18 years of age and older, male or female, any race.
3. Capacity to give informed consent and follow study procedures.
Exclusion Criteria
2. Any metal or pacemaker in the body which precludes MRI
3. Pregnancy
4. Dementia or other primary psychiatric disorders including substance abuse/dependence, anxiety disorders, schizophrenia
5. For controls, numbers one through four above as well as any history of depression or the use of antidepressants
18 Years
80 Years
ALL
Yes
Sponsors
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Duke University
OTHER
Responsible Party
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Principal Investigators
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John L Beyer, M.D
Role: PRINCIPAL_INVESTIGATOR
Duke University
Locations
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Duke University Medical Center
Durham, North Carolina, United States
Countries
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Other Identifiers
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Pro00007867
Identifier Type: -
Identifier Source: org_study_id
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