Assessment of Bifocal and Prismatic Bifocal Spectacles for Myopia Control in Children

NCT ID: NCT00787579

Last Updated: 2008-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

135 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-04-30

Brief Summary

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1. To determine if the effect of near-addition lenses (bifocals) is more prominent for children with high myopia progression.
2. To study how different subject characteristics such as age, gender, baseline degree of myopia, baseline near phoria and baseline lag of accommodation affect the efficacy of bifocal lens wear in myopic children.
3. To investigate the effect of incorporating near base-in prisms along with the near-addition lenses (prismatic bifocals) on myopia progression in myopic children.

Detailed Description

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Conditions

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Myopia

Keywords

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Myopia, bifocal, children

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Bifocal spectacles

Group Type ACTIVE_COMPARATOR

Bifocal spectacles

Intervention Type DEVICE

+1.50D bifocal spectacles

Prismatic bifocals

Group Type ACTIVE_COMPARATOR

Prismatic bifocal spectacles

Intervention Type DEVICE

+1.50D bifocal spectacles combined with 3Δ base-in prisms

Single vision spectacles

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Bifocal spectacles

+1.50D bifocal spectacles

Intervention Type DEVICE

Prismatic bifocal spectacles

+1.50D bifocal spectacles combined with 3Δ base-in prisms

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age: 8 to 13 years
* Myopia: -1.00 to -5.00 D
* Myopia progression: at least 0.50 D/yr
* Astigmatism and anisometropia: not more than 1.50 D
* Distance monocular visual acuity: 6/6 or better
* Near monocular visual acuity: 0.4 M or better
* Stereoacuity: not more than 40 sec of arc at 40 cm

Exclusion Criteria

* Strabismus
* Ocular diseases
Minimum Eligible Age

8 Years

Maximum Eligible Age

13 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Queensland University of Technology

OTHER

Sponsor Role collaborator

Essilor International

INDUSTRY

Sponsor Role lead

Responsible Party

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Essilor International

Principal Investigators

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Desmond Cheng, OD, MSc

Role: PRINCIPAL_INVESTIGATOR

Queensland University of Technology

Locations

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Dr. Desmond Cheng & Associates

Mississauga, Ontario, Canada

Site Status

Countries

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Canada

References

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Lawrenson JG, Shah R, Huntjens B, Downie LE, Virgili G, Dhakal R, Verkicharla PK, Li D, Mavi S, Kernohan A, Li T, Walline JJ. Interventions for myopia control in children: a living systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Feb 16;2(2):CD014758. doi: 10.1002/14651858.CD014758.pub2.

Reference Type DERIVED
PMID: 36809645 (View on PubMed)

Cheng D, Woo GC, Drobe B, Schmid KL. Effect of bifocal and prismatic bifocal spectacles on myopia progression in children: three-year results of a randomized clinical trial. JAMA Ophthalmol. 2014 Mar;132(3):258-64. doi: 10.1001/jamaophthalmol.2013.7623.

Reference Type DERIVED
PMID: 24435660 (View on PubMed)

Cheng D, Schmid KL, Woo GC, Drobe B. Randomized trial of effect of bifocal and prismatic bifocal spectacles on myopic progression: two-year results. Arch Ophthalmol. 2010 Jan;128(1):12-9. doi: 10.1001/archophthalmol.2009.332.

Reference Type DERIVED
PMID: 20065211 (View on PubMed)

Other Identifiers

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Essilor

Identifier Type: -

Identifier Source: org_study_id