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A Study of the Association Between Tobacco Smoking and Bipolar Affective Disorder

NCT ID: NCT00741299

Last Updated: 2012-07-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-08-31

Study Completion Date

2009-09-30

Brief Summary

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The purpose of this study is to examine whether tobacco smoking is associated with bipolar affective disorder (severity of depressive and manic symptoms, presence of psychotic symptoms, history of a suicide attempts and other clinical features.)

Detailed Description

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An association exists between smoking and schizophrenia, independent of other factors and related to psychotic symptomatology. Only a few small descriptive studies have examined the prevalence and correlates of tobacco use among bipolar patients with conflicting results. Patients who smoke score higher on rating scales for psychotic symptoms than their non-smoking peers. While the association of smoking with psychotic symptomatology in schizophrenia is established, such association according to bipolar affective disorder has been reported in a few studies and remains unclear. Also a few studies reported about association of smoking with depressive and manic symptoms, and with suicidal behavior in bipolar patients. Thus further investigation of these issues is warranted.

Conditions

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Bipolar Disorder

Keywords

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bipolar affective disorder, Smoking

Study Design

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Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age 18-65 male or female
* DSM -IV criteria for bipolar I affective disorder
* Ability and willingness to sign informed consent for participation in the study

Exclusion Criteria

* Unwillingness or inability to participate in the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tirat Carmel Mental Health Center

OTHER_GOV

Sponsor Role lead

Responsible Party

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Anatoly Dr. Kreinin

Director of psychiatric department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Anatoly Kreinin, MD, PHD

Role: PRINCIPAL_INVESTIGATOR

B. Rappaport Faculty of Medicine, Technion, Haifa

Locations

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Tirat Carmel Mental Health Center

Tirat HaCarmel, Tirat HaCarmel, Israel

Site Status

Countries

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Israel

References

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Kreinin A, Novitski D, Rabinowitz D, Weizman A, Grinshpoon A. Association between tobacco smoking and bipolar affective disorder: clinical, epidemiological, cross-sectional, retrospective study in outpatients. Compr Psychiatry. 2012 Apr;53(3):269-74. doi: 10.1016/j.comppsych.2011.04.063. Epub 2011 Jun 12.

Reference Type DERIVED
PMID: 21664608 (View on PubMed)

Other Identifiers

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GKN2007

Identifier Type: -

Identifier Source: secondary_id

GKN2007

Identifier Type: -

Identifier Source: org_study_id