Bevacizumab Treatment and Retinal Vessel Monitoring

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-05-31

Study Completion Date

2009-04-30

Brief Summary

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Bevacizumab might influence the dynamic vessel function after being administered intravenously.

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Detailed Description

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By monitoring different vessel and circulation parameters (e.g. dynamic retinal vessel analyzer) the study will clarify the potential hemodynamic effects of bevacizumab.

Conditions

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Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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TG

Bevacizumab treatment group with metastasized cancer

bevacizumab treatment

Intervention Type DRUG

single infusion 10 mg/kg

Interventions

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bevacizumab treatment

single infusion 10 mg/kg

Intervention Type DRUG

Other Intervention Names

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Avastin ATC code: L01XC07 CAS Registry Number:216974-75-3 VEGF-inhibitor

Eligibility Criteria

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Inclusion Criteria

* patients who wish and need bevacizumab treatment for underlying disease

Exclusion Criteria

* previous bevacizumab treatment
* known eye disease, eye surgery or eye trauma in history
* myopia \>-2.0 dpt
* hyperopia \> +2.0 dpt.
* relevant media opacity of the lens
* acute heart disease, ischemic insult, proven coronary heart disease
* cardiac arrhythmia or vessel anomalies
* seizure disorder or episode in history
* migraine
* treatment with corticosteroids within 4 weeks before study inclusion
* intake of vasoactive drugs like AT-1 or glitazone
* pregnancy

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No