Compliance of HCV Genotype 1 Infected Patients Receiving PegIntron/Rebetol and a Patient Assistance Program (Study P04671)

NCT ID: NCT00728494

Last Updated: 2015-07-28

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

99 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-10-31

Study Completion Date

2007-12-31

Brief Summary

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Enrolled patients will be recruited to two parallel groups during therapy for Hepatitis C. Patients in the first one will receive a patient assistance program, and patients in the second group will not. All patients will receive PegIntron and Rebetol according to label.

Detailed Description

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Non-Probability Sample, Commercial product used according to EU label.

Conditions

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Hepatitis C, Chronic Hepatitis C

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Treatment and Patient Assistance Program

Patient assistance program was provided to the participants treated with PegIntron/Rebetol. The support program consisted of training by physicians or specialized nurses on the significance of treatment compliance, methods for managing adverse events, and correct drug administration, as well as informational materials and assistance in the management of adverse events.

PegIntron (peginterferon alfa-2b; SCH 54031)

Intervention Type BIOLOGICAL

Peginterferon alfa-2b will be administered according to the product's labeling.

Rebetol (ribavirin; SCH 18908)

Intervention Type DRUG

Ribavirin will be administered according to the product's labeling.

Patient Assistance Program

Intervention Type BEHAVIORAL

The patient assistance program includes the following:

* Training by physicians or specialized nurses.
* Informational materials based on the "To beat HCV" program.
* Management of specific side effects.

Treatment Alone

PegIntron/Rebetol treatment only.

PegIntron (peginterferon alfa-2b; SCH 54031)

Intervention Type BIOLOGICAL

Peginterferon alfa-2b will be administered according to the product's labeling.

Rebetol (ribavirin; SCH 18908)

Intervention Type DRUG

Ribavirin will be administered according to the product's labeling.

Interventions

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PegIntron (peginterferon alfa-2b; SCH 54031)

Peginterferon alfa-2b will be administered according to the product's labeling.

Intervention Type BIOLOGICAL

Rebetol (ribavirin; SCH 18908)

Ribavirin will be administered according to the product's labeling.

Intervention Type DRUG

Patient Assistance Program

The patient assistance program includes the following:

* Training by physicians or specialized nurses.
* Informational materials based on the "To beat HCV" program.
* Management of specific side effects.

Intervention Type BEHAVIORAL

Other Intervention Names

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PegIntron Rebetol Support program

Eligibility Criteria

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Inclusion Criteria

* According to PegIntron/Rebetol label.
* Only HCV genotype 1 infected patients will be enrolled in the study.

Exclusion Criteria

* According to PegIntron/Rebetol label.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Merck Sharp & Dohme LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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P04671

Identifier Type: -

Identifier Source: org_study_id

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