Trial Outcomes & Findings for PC-Based Rehabilitation of Auditory Function (NCT NCT00724347)
NCT ID: NCT00724347
Last Updated: 2015-01-27
Results Overview
Mean consonant identification threshold improvement measure in z-scores (re normal hearing subjects) on consonant and sentence discrimination tests. Additional computerized tests measured auditory short-term verbal memory, and auditory pattern discrimination. The results were compared with baseline performance in the listener group as well as performance in other older hearing impaired subjects who used hearing aids, but who did not undergo training. In the next month, we will published two manuscripts in PLoS ONE describing (1) the benefits of hearing aids on speech comprehension in the absence of perceptual training; (2) the additional benefits of perceptual training. More metholdological details can be found in those manuscripts.
COMPLETED
NA
18 participants
Subjects will receive two months of PC training and be tested before and after 2-months of training with speech tests in the laboratory..
2015-01-27
Participant Flow
VA patients with hearing loss who wore hearing aids (HAs) were recruited from the VA audiology clinic. Control subjects of similar ages as well as young control subjects were also recruited in order to characaterize speech discrimination capabilities in normal-hearing populations.
Most listeners with hearing loss were tested with and without their hearing aids prior to beginning 8 weeks of at-home PC training.
Participant milestones
| Measure |
Arm 1
PC-Based Consonant Discrimination Training: Subjects will receive adaptive training in consonant discrimination on PCs in their homes.
|
|---|---|
|
Overall Study
STARTED
|
18
|
|
Overall Study
Baseline Testing
|
18
|
|
Overall Study
COMPLETED
|
16
|
|
Overall Study
NOT COMPLETED
|
2
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
PC-Based Rehabilitation of Auditory Function
Baseline characteristics by cohort
| Measure |
Training Group
n=18 Participants
Hearing impaired subjects with bilateral, symmtrical sloping hearing losses who wore hearing aids
|
|---|---|
|
Age, Continuous
|
65.67 years
STANDARD_DEVIATION 6.51 • n=5 Participants
|
|
Age, Categorical
<=18 years
|
0 Participants
n=5 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
9 Participants
n=5 Participants
|
|
Age, Categorical
>=65 years
|
9 Participants
n=5 Participants
|
|
Sex: Female, Male
Female
|
0 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
18 Participants
n=5 Participants
|
|
Region of Enrollment
United States
|
18 participants
n=5 Participants
|
|
Audiometry
Thresholds 500 Hz
|
19.69 Sound intensity dB HL
STANDARD_DEVIATION 13.35 • n=5 Participants
|
|
Audiometry
Thresholds 1000 Hz
|
29.38 Sound intensity dB HL
STANDARD_DEVIATION 16.42 • n=5 Participants
|
|
Audiometry
Thresholds 2000 Hz
|
43.13 Sound intensity dB HL
STANDARD_DEVIATION 15.15 • n=5 Participants
|
|
Audiometry
Thresholds 4000 Hz
|
66.88 Sound intensity dB HL
STANDARD_DEVIATION 9.46 • n=5 Participants
|
|
Audiometry
Thresholds 6000 Hz
|
71.25 Sound intensity dB HL
STANDARD_DEVIATION 12.58 • n=5 Participants
|
PRIMARY outcome
Timeframe: Subjects will receive two months of PC training and be tested before and after 2-months of training with speech tests in the laboratory..Population: older hearing impaired listeners with hearing aids.
Mean consonant identification threshold improvement measure in z-scores (re normal hearing subjects) on consonant and sentence discrimination tests. Additional computerized tests measured auditory short-term verbal memory, and auditory pattern discrimination. The results were compared with baseline performance in the listener group as well as performance in other older hearing impaired subjects who used hearing aids, but who did not undergo training. In the next month, we will published two manuscripts in PLoS ONE describing (1) the benefits of hearing aids on speech comprehension in the absence of perceptual training; (2) the additional benefits of perceptual training. More metholdological details can be found in those manuscripts.
Outcome measures
| Measure |
Training Group
n=16 Participants
Hearing impaired subjects with bilateral, symmtrical sloping hearing losses who wore hearing aids
|
|---|---|
|
.Speech Discrimination Ability
Improvement in consonant thresholds
|
9.43 signal to noise ratio in dB SNR
Standard Deviation 4.84
|
|
.Speech Discrimination Ability
Improvement in sentence thresholds
|
0.46 signal to noise ratio in dB SNR
Standard Deviation 1.23
|
Adverse Events
Arm 1
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place