Adolescent Substance Abuse: Progressive Treatment

NCT ID: NCT00680576

Last Updated: 2014-10-10

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE1
• Total Enrollment: 140 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2008-03-31
• Study Completion Date: 2013-08-31

Brief Summary

The purpose of this study is to find out more about how to provide effective further treatment for adolescents who have received six weeks of group therapy for substance-use problems and continue to use drugs. Treatments used in the study include a group therapy (MET/CBT), an individual therapy (CBT), and a family therapy (FFT). The study will look at whether abstinence or a very low level of use is a better guide for deciding whether further treatment is needed, how well different combinations of treatment work to reduce substance use, and whether it is possible to predict in advance which adolescents will respond best to which types of treatment. Study investigators expect that a treatment strategy using what is learned about these issues in the first half of the project to develop an "adaptive" treatment model will work better than a "fixed" treatment to reduce adolescent substance use.

Conditions

Substance Abuse

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: FACTORIAL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

1

Eight weeks of individual CBT for adolescents who have completed six weeks of group therapy and continue to use drugs.

Group Type: ACTIVE_COMPARATOR

CBT, Cognitive Behavioral Therapy

Intervention Type: BEHAVIORAL

Eight weekly sessions of individual Cognitive Behavioral Therapy, to develop skills enabling adolescents stop or reduce their drug use.

2

Eight weeks of FFT for adolescents who have received six weeks of group therapy and continue to use drugs.

Group Type: ACTIVE_COMPARATOR

FFT, Family Functional Therapy

Intervention Type: BEHAVIORAL

Eight weekly sessions of Functional Family Therapy designed to strengthen family relationships and build skills to help the adolescent stop or reduce his/her drug use.

Interventions

CBT, Cognitive Behavioral Therapy

Eight weekly sessions of individual Cognitive Behavioral Therapy, to develop skills enabling adolescents stop or reduce their drug use.

Intervention Type: BEHAVIORAL

FFT, Family Functional Therapy

Eight weekly sessions of Functional Family Therapy designed to strengthen family relationships and build skills to help the adolescent stop or reduce his/her drug use.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

1. 13 to 18 years if age

2. Meet DSM-IV (APA, 1994) diagnostic criteria for substance abuse or dependence

3. Live in the Albuquerque metropolitan area or surrounding communities

4. Sufficient residential stability to permit probable contact at follow-up (e.g., not homeless at time of intake).

Exclusion Criteria

1. There is evidence of psychotic or organic state of sufficient severity to interfere with the understanding of study instruments and procedures

2. The adolescent is deemed dangerous to self or others during evaluation

3. Services other than outpatient treatment are required for the adolescent (e.g., inpatient, detoxification)

4. Marijuana use is reported as being less than 13% of days in the previous 90 days.

• Minimum Eligible Age: 13 Years
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Oregon Research Institute

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Holly B Waldron, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Oregon Research Institute Center for Family and Adolescent Research (ORI/CFAR)

Locations

Oregon Res. Inst. Center for Family & Adolescent Research (CFAR)

Albuquerque, New Mexico, United States

Countries

United States

Other Identifiers

R01DA023568

Identifier Type: NIH

Identifier Source: secondary_id

View Link

DA023568

Identifier Type: -

Identifier Source: org_study_id