Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
963 participants
OBSERVATIONAL
2007-09-30
2017-03-27
Brief Summary
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* Peripheral blood
* Bone marrow
* Bone marrow biopsy
* A phlebotomized unit of blood
* Spleen cells
* Toenail clippings
This material will be used for the study of Myeloproliferative Disorders (MPD) by researchers. The goals of this research study are to understand the causes of MPDs, how to diagnose them more easily and how to treat them better. MPD is a disease affecting hematopoietic stem cells. Hematopoietic stem cells are cells that make blood cells. These stem cells grow in the center portion of the bones called bone marrow. Under some conditions, these cells are also found in blood. There are several diseases, which are classified as MPD. These include polycythemia vera (too many red blood cells), essential thrombocythemia (too many platelets), and idiopathic myelofibrosis (abnormal blood cells and fibers build up in the bone marrow). These syndromes carry a high risk of developing leukemia. It is important to continue to learn more about these blood cancers and to learn more about the effectiveness and potential side effects of various treatments.
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Detailed Description
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Conditions
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Study Design
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OTHER
OTHER
Eligibility Criteria
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Inclusion Criteria
* Newly diagnose MPD patients as well as previously treated for a MPD are eligible.
* Signed informed consent is required from each patient at the time of enrollment.
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Myeloproliferative Disorders-Research Consortium
NETWORK
National Cancer Institute (NCI)
NIH
Icahn School of Medicine at Mount Sinai
OTHER
Responsible Party
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Principal Investigators
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Rona S Weinberg, PhD
Role: STUDY_CHAIR
Myeloproliferative Disorders-Research Consortium
Lewis Silverman, MD
Role: PRINCIPAL_INVESTIGATOR
Icahn School of Medicine at Mount Sinai
Locations
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Palo Alto Medical Foundation Research Institute
Palo Alto, California, United States
Weill Cornell University
Washington D.C., District of Columbia, United States
University of Georgetown
Washington D.C., District of Columbia, United States
University of Illinois at Chicago
Chicago, Illinois, United States
Johns Hopkins
Baltimore, Maryland, United States
Roswell Park
Buffalo, New York, United States
Mount Sinai Medical Center
New York, New York, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
University of Utah
Salt Lake City, Utah, United States
Ospedali Riuniti di Bergamo
Bergamo, IL, Italy
University of Florence
Florence, IL, Italy
Countries
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Other Identifiers
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MPD-RC 106
Identifier Type: OTHER
Identifier Source: secondary_id
GCO 07-0548-00106
Identifier Type: -
Identifier Source: org_study_id
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