Collecting Blood and Tissue Samples From Family Members of Patients With Pancreatic Diseases, Pancreatic Cancer, and Melanoma

NCT ID: NCT00835133

Last Updated: 2025-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

1122 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-08-01

Study Completion Date

2026-09-30

Brief Summary

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RATIONALE: Collecting and storing samples of blood and tissue from family members of patients with cancer to test in the laboratory may help the study of cancer in the future.

PURPOSE: This clinical trial is collecting blood and tissue samples from family members of patients with pancreatic disease, pancreatic cancer, and melanoma.

Detailed Description

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OBJECTIVES:

* To collect clinical history, family history, and blood and/or tissue samples from family members of patients diagnosed with pancreatic diseases, pancreatic cancer, or melanoma.
* To learn whether inherited factors increase the risk of pancreatic diseases, pancreatic cancer, or other cancers.

OUTLINE: Study participants undergo collection of blood and/or tissue samples as well as survey data for inclusion in a familial data and tissue registry. Participants complete two baseline surveys regarding their personal, family, health, and environmental exposure histories and regarding their opinions on cancer and cancer screening. Patients also complete a follow-up survey at 1 year and undergo review of their medical records.

Conditions

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Familial Pancreatic Cancer

Study Design

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Observational Model Type

FAMILY_BASED

Study Time Perspective

PROSPECTIVE

Interventions

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biologic sample preservation procedure

one blood sample

Intervention Type OTHER

medical chart review

confirmation of cancer diagnosis

Intervention Type OTHER

survey administration

at baseline enrollment and 12 months post-enrollment

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

DISEASE CHARACTERISTICS:

* Meets 1 of the following criteria:

* Has at least 2 blood relatives with pancreatic cancer (both must be related)
* Has at least 1 blood relative with pancreatic cancer and 1 with melanoma (both must be related)

PATIENT CHARACTERISTICS:

* Mentally competent and able to provide informed consent
* Able to understand and read English

PRIOR CONCURRENT THERAPY:

* Not specified
Minimum Eligible Age

18 Years

Maximum Eligible Age

120 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Shounak Majumder

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Shounak Majumder, M.D.

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic Cancer Center

Rochester, Minnesota, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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R01CA097075-08

Identifier Type: NIH

Identifier Source: secondary_id

View Link

CDR0000613097

Identifier Type: REGISTRY

Identifier Source: secondary_id

355-06

Identifier Type: -

Identifier Source: org_study_id

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