Monitoring and Evaluation of Micronutrients (Sprinkles) Project

NCT ID: NCT00659061

Last Updated: 2018-02-01

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

610 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-08-31

Study Completion Date

2008-05-31

Brief Summary

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The purpose of this study is 1) to evaluate the effectiveness in reducing anemia among children 6-24 months of age by providing daily micronutrient Sprinkles through the Government of Pakistan's Lady Health Worker program; 2) to assist in the monitoring the National Sprinkles Pilot Project.

Detailed Description

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According to the recent National Nutrition Survey in Pakistan (2001-2002), approximately 66.5% of children under five have anaemia.

Looking at the magnitude of the problem, National Program for Family Planning (FP) and Primary Health Care (PHC) (also known as the Lady Health Workers (LHW) Program) has developed National Sprinkles Pilot Project Proposal with technical assistance of Micronutrient Initiative and Aga Khan University (AKU). As the projects technical partner, AKU is responsible to conduct the monitoring and evaluation of the project.

The study will use a cluster randomized pre-post intervention design that compares before and after hemoglobin (Hb) measurements, serum ferritin, serum retinol and urinary iodine among children who received Sprinkles and age-appropriate feeding advice (Sprinkles-Advice group) and children who only receive age-appropriate feeding advice (Advice-only group). Age-appropriate feeding advice is part of the standard nutrition messages given by all Lady Health Workers (LHWs) during their community visits. However, intervention LHWs, will give additional advice regarding the benefits of Sprinkles and its appropriate use.

The target population selected for the study consisted of children between the ages of six and eighteen months of age in the catchment area of the Lady Health Workers.

Conditions

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Anemia

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Intervention

Multiple micronutrient fortificant (Sprinkles) and nutrition education given by LHWs.

Group Type ACTIVE_COMPARATOR

SPRINKLES

Intervention Type DIETARY_SUPPLEMENT

Sprinkles is a multiple micronutrient fortificant. It is packed as a single serving sachets each containing micro encapsulated iron (12.5 mg), zinc (7.5 mg), vitamin C (30 mg), vitamin A (300 µg), vitamin D (5 µg), folic acid (150 µg) and iodine (90µg).

Two month supply of the Sprinkle sachet along with advice on its benefits as well as its appropriate use will be given by the LHWs. The LHWs will also provide their age-appropriate nutritional advice as per their regular door to door community services.

Nutrition education

Intervention Type BEHAVIORAL

Nutrition education will be provided by LHWs as per their regular routine monthly door to door community services

Control

Routine public health massages by Lady Health Workers (LHWs) during their community visits.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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SPRINKLES

Sprinkles is a multiple micronutrient fortificant. It is packed as a single serving sachets each containing micro encapsulated iron (12.5 mg), zinc (7.5 mg), vitamin C (30 mg), vitamin A (300 µg), vitamin D (5 µg), folic acid (150 µg) and iodine (90µg).

Two month supply of the Sprinkle sachet along with advice on its benefits as well as its appropriate use will be given by the LHWs. The LHWs will also provide their age-appropriate nutritional advice as per their regular door to door community services.

Intervention Type DIETARY_SUPPLEMENT

Nutrition education

Nutrition education will be provided by LHWs as per their regular routine monthly door to door community services

Intervention Type BEHAVIORAL

Other Intervention Names

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Multiple micronutrient fortificant

Eligibility Criteria

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Inclusion Criteria

* Child's mother gives written consent after hearing an explanation of the study
* Random selection of child in household with more than one eligible child

Exclusion Criteria

* Any household in which consent is not given
* Children with any congenital or physical disability (such as cleft palate, Down's Syndrome, etc.)
* Child from a family which intends to migrate during the study period
Minimum Eligible Age

6 Months

Maximum Eligible Age

18 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Micronutrient Initiative

OTHER

Sponsor Role collaborator

M/S SEBCON

OTHER

Sponsor Role collaborator

Pakistan Ministry of Health

OTHER_GOV

Sponsor Role collaborator

National Programme of Family Planning and Primary Health Care

UNKNOWN

Sponsor Role collaborator

Aga Khan University

OTHER

Sponsor Role lead

Responsible Party

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Dr Zulfiqar Ahmed Bhutta

Founding Director, Centre of Excellence in Women and Child Health

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Zulfiqar A Bhutta, MD, PhD

Role: STUDY_CHAIR

Aga Khan University

Locations

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AKU-Peds Naushero Feroze Site Office

Naushero Feroze, Sindh, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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754-Ped/ERC-07

Identifier Type: -

Identifier Source: org_study_id

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