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Effects of Whole-Body Vibration Exercise on Serum IGF-1 in Fibromyalgia

NCT ID: NCT00650715

Last Updated: 2008-04-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-12-31

Study Completion Date

2005-01-31

Brief Summary

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The purpose of this study was to investigate the acute and chronic effect of whole-body vibration exercise on serum insulin-like growth factor-1 levels in women with fibromyalgia (FM). It was hypothesized that women with FM would exhibit an increase in IGF-1 following both acute and chronic WBV. Twenty-four women with FM were randomized into two groups: Vibration Group (VG) and Control Group (CG). The VG underwent a protocol with WBV exercise twice a week for a total of six weeks, whereas the CG performed the same protocol without vibratory stimulus. Both groups continued with their usual pharmacological treatment. Serum IGF-1 levels were determined using Enzyme-Linked Immunosorbent Assay (ELISA). To test the effect of chronic WBV, serum IGF-1 measurements were taken at baseline and at weeks 1,3, and 6 of intervention. To test the effect of acute WBV, within week 1, serum IGF-1 measurements were taken before and immediately following a session of WBV.

Detailed Description

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Conditions

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Fibromyalgia Hormonal Responses to Exercise in Patients With Fibromyalgia.

Keywords

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Fibromyalgia Whole-Body vibration Exercise IGF-1

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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VG

Vibration Group (VG) underwent a protocol with whole-body vibration exercise twice a week for a total of six weeks. The group continued with their usual pharmacological treatment.

Group Type ACTIVE_COMPARATOR

Vibratory platform, PowerPlate®, Badhoevendorp, Netherlands

Intervention Type DEVICE

Six exercises (static and dynamic tasks) while standing on a Whole-body vibration platform. The six exercises (30 seconds each) were repeated six times with a recovery of 3 minutes in between. The Whole-body vibration intensity was kept constant at 30 Hz of frequency and 2 mm of amplitude.

CG

The Control Group (CG) underwent the same protocol of exercises than VG but without vibratory stimulus. The CG continued with their usual pharmacological treatment.

Group Type PLACEBO_COMPARATOR

Placebo Whole-body vibration exercise

Intervention Type DEVICE

Six exercises (static and dynamic tasks) while standing on a Whole-body vibration platform. The six exercises (30 seconds each) were repeated six times with a recovery of 3 minutes in between. All exercises were performed without the influence of a vibratory stimulus.

Interventions

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Vibratory platform, PowerPlate®, Badhoevendorp, Netherlands

Six exercises (static and dynamic tasks) while standing on a Whole-body vibration platform. The six exercises (30 seconds each) were repeated six times with a recovery of 3 minutes in between. The Whole-body vibration intensity was kept constant at 30 Hz of frequency and 2 mm of amplitude.

Intervention Type DEVICE

Placebo Whole-body vibration exercise

Six exercises (static and dynamic tasks) while standing on a Whole-body vibration platform. The six exercises (30 seconds each) were repeated six times with a recovery of 3 minutes in between. All exercises were performed without the influence of a vibratory stimulus.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed of fibromyalgia according to the American College of Rheumatology criteria for at least three years.

Exclusion Criteria

* Orthopedic limitation, or cardiovascular, pulmonary, or metabolic disease that would preclude exercise.
* Participation in any other study.
Minimum Eligible Age

35 Years

Maximum Eligible Age

69 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Institut Nacional d'Educacio Fisica de Catalunya

OTHER

Sponsor Role lead

Responsible Party

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INEFC

Principal Investigators

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Eduard Alentorn-Geli, MD

Role: PRINCIPAL_INVESTIGATOR

INEFC

Locations

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Institut Nacional d'Educación Física de Catalunya

Barcelona, Barcelona, Spain

Site Status

Countries

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Spain

Other Identifiers

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WBVIGF1FM

Identifier Type: -

Identifier Source: org_study_id