The Effect of Myopic Optical Defocus on the Humphrey Matrix 30-2 Test

NCT ID: NCT00638430

Last Updated: 2008-03-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-03-31

Study Completion Date

2008-03-31

Brief Summary

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The purpose of this study is to examine the effect of the myopic optical defocus on the Humphrey Matrix 30-2 test.

Detailed Description

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The Humphery Matrix (Zeiss, Dublin, California, USA; in cooperation with Welch Allyn, Skaneateles, New York, USA), which is a recently developed version of FDT perimetry, showed more improved technology to detect early glaucomatous damage. The user's guide for the Humphrey Matrix (Humphrey® matrix visual field instrument user's guide. Zeiss, Dublin, California, USA; in cooperation with Welch Allyn, Skaneateles, New York, USA; 2003) suggests that myopic refractive errors more than -3.0 D need to be corrected before the 30-2 test. However, the proper correction of the optical defocus is not always easy because of a lack of trial frame.

The purpose of the present study is twofold. At first, the influence of the low-grade myopia on the Humphery Matrix 30-2 test will be evaluated and compared to the effect of moderate-grade myopia. Secondly, the influence of myopic optical defocus and the glaucomatous visual field damage on the pattern deviation plot change according to the severity of glaucomatous visual field damage will be estimated.

Conditions

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Myopia

Keywords

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myopia Humphery Matrix 30-2 test

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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1

low myopic group

No interventions assigned to this group

2

moderate myopic group

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* intra-ocular pressure 23 or higher
* suspicious glaucomatous optic disc change
* suspicious defect of retinal nerve fiber layer
* or eyes with various degrees of glaucoma

Exclusion Criteria

* a high myopic eye (SE more than -6.0 D)
* moderate to severe cataract
* evidence of diabetic or hypertensive retinopathy
* macular disease
* intra-ocular inflammation
* history of intraocular surgery and any other ocular lesion that could have an influence on the perimetry result
Minimum Eligible Age

27 Years

Maximum Eligible Age

61 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Department of Ophthalmology, Samsung Medical Center,

Principal Investigators

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Changwon Kee, M.D.

Role: STUDY_CHAIR

Department of Ophthalmology, Samsung Medical Center,

Locations

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Samsung Medical Center

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Anderson AJ, Johnson CA. Frequency-doubling technology perimetry and optical defocus. Invest Ophthalmol Vis Sci. 2003 Sep;44(9):4147-52. doi: 10.1167/iovs.02-1076.

Reference Type RESULT
PMID: 12939339 (View on PubMed)

Other Identifiers

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Humphrey30-2

Identifier Type: -

Identifier Source: org_study_id