Genetics of Spina Bifida and Anencephaly

NCT ID: NCT00636233

Last Updated: 2020-04-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

1993-05-31

Study Completion Date

2017-08-02

Brief Summary

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The goal of this research study is to discover the genetic and environmental factors that contribute to the cause of neural tube defects such as spina bifida and anencephaly. Ultimately, this type of research may result in improved diagnosis, improved treatment and possibly prevention.

Detailed Description

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Conditions

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Anencephaly Acrania

Study Design

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Observational Model Type

FAMILY_BASED

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Anencephaly

Fetuses with anencephaly, parents and siblings

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

Not currently enrolling new participants.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Neurological Disorders and Stroke (NINDS)

NIH

Sponsor Role collaborator

Duke University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Allison Ashley-Koch, PhD

Role: PRINCIPAL_INVESTIGATOR

Duke Health

Locations

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Duke University Medical Center

Durham, North Carolina, United States

Site Status

Countries

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United States

Related Links

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http://dmpi.duke.edu/anencephaly

Anencephaly study description

http://dmpi.duke.edu/neural-tube-defects-ntds

Neural tube defect study description

Other Identifiers

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R01NS039818

Identifier Type: NIH

Identifier Source: secondary_id

View Link

Pro00016517

Identifier Type: -

Identifier Source: org_study_id

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