Pentoxifylline and Endometriosis

NCT ID: NCT00632697

Last Updated: 2008-03-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

104 participants

Study Classification

INTERVENTIONAL

Study Start Date

2001-10-31

Study Completion Date

2006-12-31

Brief Summary

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To prove efficacy of an immunomodulator called pentoxifylline in the treatment of endometriosis in infertile patients undergoing laparoscopy surgery

Detailed Description

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Conditions

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Endometriosis-Associated Infertility

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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1

Group Type ACTIVE_COMPARATOR

pentoxifylline

Intervention Type DRUG

800 mg daily for six months

2

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DRUG

Interventions

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pentoxifylline

800 mg daily for six months

Intervention Type DRUG

placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Infertile patients having early endometriosis as the only factor of their infertility

Exclusion Criteria

* Previous treatment for endometriosis or patients having pelvic disorders in addition to endometriosis
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Hospital Clinic of Barcelona

OTHER

Sponsor Role lead

Locations

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Hospital Clinic

Barcelona, Barcelona, Spain

Site Status

Countries

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Spain

References

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Creus M, Fabregues F, Carmona F, del Pino M, Manau D, Balasch J. Combined laparoscopic surgery and pentoxifylline therapy for treatment of endometriosis-associated infertility: a preliminary trial. Hum Reprod. 2008 Aug;23(8):1910-6. doi: 10.1093/humrep/den167. Epub 2008 May 16.

Reference Type DERIVED
PMID: 18487215 (View on PubMed)

Other Identifiers

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LETS

Identifier Type: -

Identifier Source: org_study_id

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