Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
34 participants
INTERVENTIONAL
Brief Summary
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This study aims to investigate the effect of doxycycline treatment on lateral epicondylalgia (tennis elbow). During three weeks, patients receive doxycycline tablets 100 mg twice daily, or placebo. Main outcome variable is pain (VAS) at three weeks.
Serum and/or plasma levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases are measured.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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2
Placebo
Doxycycline
100 mg twice daily
Doxycycline
Interventions
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Placebo
Doxycycline
Eligibility Criteria
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Inclusion Criteria
* Pain at the lateral side of the elbow ≥8 weeks
* Local tenderness on palpation of the lateral epicondyle
* Pain on resisted extension of the wrist
Exclusion Criteria
* History of fibromyalgia or generalised pain
* Elbow surgery (on the painful side)
* Active infection
* Glucocorticoid treatment during the duration of symtoms of epicondylalgia
* NSAID use within 1 w before presentation and during the study
* Pregnancy
* Taking drug that might interact with doxycycline
18 Years
65 Years
ALL
No
Sponsors
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University Hospital, Linkoeping
OTHER
Kaunas University of Medicine
OTHER
Responsible Party
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Dept of Orthopaedics, University Hospital Linkoeping
Locations
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Dept of Orthopaedics, Kaunas Medical University
Kaunas, Kaunas County, Lithuania
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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BE-2-47
Identifier Type: -
Identifier Source: org_study_id
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