Testing Strategies to Improving Warfarin Adherence

NCT ID: NCT00622102

Last Updated: 2009-12-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

101 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-12-31

Study Completion Date

2009-04-30

Brief Summary

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We are performing a research study to learn more about the control of an individual's blood thinning (anticoagulation) on warfarin. Individuals from an anticoagulation clinic are being asked to participate in order to see if a lottery which provides the opportunity to win money in combination with the use of the Med-eMonitor might be useful in helping patients to achieve better control of their anticoagulation therapy. Half of the participants will be enrolled in the lottery arm and the other half will be a control group who will receive the Med-eMonitor only.

Detailed Description

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Conditions

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Atrial Fibrillation Deep Venous Thrombosis Dilated Cardiomyopathies

Keywords

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warfarin adherence Mechanical heart valves

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Investigators

Study Groups

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1

50% of the consenting subjects will take part in the lottery and use the Med-eMonitor as a device to monitor adherence

Group Type EXPERIMENTAL

Lottery arm (Lottery and Med-eMonitor)

Intervention Type BEHAVIORAL

Lottery and Med-eMonitor

2

50% of the consenting subjects will use only the Med-eMonitor as a device to monitor adherence

Group Type OTHER

Non-Lottery (Med-eMonitor only)

Intervention Type BEHAVIORAL

Med-eMonitor only

Interventions

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Lottery arm (Lottery and Med-eMonitor)

Lottery and Med-eMonitor

Intervention Type BEHAVIORAL

Non-Lottery (Med-eMonitor only)

Med-eMonitor only

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 21 years old age or older
* On warfarin managed at the AC clinic
* Target INR 2.0-3.0 or 2.5-3.5
* At maintenance phase of therapy (defined as stable INR with stable warfarin dosing over at least 2 consecutive visits)

Exclusion Criteria

* Do not have access to telephone line
* Unwillingness to participate or to sign a consent form(refusal)
* Inability to participate because of advances dementia, advanced Alzheimer's disease or other impairment affecting ability to provide informed consent and/or quality data or utilize the Med-eMonitor
* Participation in a current study that does not permit participation in another study
* End stage or terminal illness with anticipated life expectancy of 6 months or less
* INR over the upper limit for the individual's range at the time of enrollment (e.g.,\>3.0 or \>3.5, depending on the target range)
* Diagnosed with antiphospholipid antibody syndrome or abnormal INR prior to starting warfarin
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aetna, Inc.

INDUSTRY

Sponsor Role collaborator

University of Pennsylvania

OTHER

Sponsor Role lead

Responsible Party

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University of Pennsylvania School of Medicine

Principal Investigators

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Kevin G Volpp, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Pennsylvania

Locations

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Hospital of the University of Pennsylvania Anticoagulation Management Center

Philadelphia, Pennsylvania, United States

Site Status

Countries

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United States

Other Identifiers

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806634

Identifier Type: -

Identifier Source: org_study_id