Bilateral, Masked Comparison of PEG-400 Based Artificial Tear and Systane for the Treatment of Dry Eye Signs, Symptoms and Visual Quality

NCT ID: NCT00622037

Last Updated: 2010-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-02-29

Study Completion Date

2008-05-31

Brief Summary

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To evaluate and compare the effects of PEG-400 based artificial tear and Systane tears in mild-moderate dry eye patients. TBUT, Visual impact and subjective evaluations will be assessed in this month long trial.

Detailed Description

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Conditions

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Dry Eye

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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1

PEG-400 based artificial tear

Group Type ACTIVE_COMPARATOR

PEG-400 based artificial tear

Intervention Type DRUG

Instill one drop in the randomized eye four times daily. Can be used more frequently if needed

2

Systane

Group Type ACTIVE_COMPARATOR

Systane

Intervention Type DRUG

Instill one drop in the randomized eye four times daily. Can be used more frequently if needed

Interventions

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PEG-400 based artificial tear

Instill one drop in the randomized eye four times daily. Can be used more frequently if needed

Intervention Type DRUG

Systane

Instill one drop in the randomized eye four times daily. Can be used more frequently if needed

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patient reported dry eye symptoms (episodic, annoying, activity limiting), SES OD.
* Physician assessment of mild-moderate dry eye
* Patient willing to instill drops QID and complete entire length of protocol.
* TBUT \< 10 seconds
* BCVA of 20/30 or better

Exclusion Criteria

* Current topical cyclosporine use (Restasis)
* Current Systane use
* Refractive surgery within the last 6 months
* Oral or topical corticosteroid use
* Severe dry eye patients by physician assessment
* current active Blepharitis
* Oral Doxycyclines use
* Oral Antihistamine use
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Bp Consulting, Inc

NETWORK

Sponsor Role lead

Responsible Party

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Florida Microsurgical Eye Institute

Principal Investigators

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Barry Schechter, MD

Role: PRINCIPAL_INVESTIGATOR

Florida Microsurgical Eye Institute

Locations

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Florida Microsurgical Eye Institute

Boynton Beach, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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5338

Identifier Type: -

Identifier Source: org_study_id

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