Efficacy of Nonsteroidal Anti-inflammatory Drugs in Treatment of Moderate and Severe Dry Eye Disease
NCT ID: NCT01562795
Last Updated: 2014-01-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
48 participants
INTERVENTIONAL
2012-03-31
2012-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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group 1
nonsteroid anti-inflammatory drops
nonsteroid anti-inflammatory drops plus artificial tear substitute
group 2
nonsteroid anti-inflammatory drops
nonsteroid anti-inflammatory drops plus artificial tear substitute
group 3
corticosteroids
corticosteroids plus artificial tear substitute
group 4
artificial tear substitute
artificial tear substitute alone
Interventions
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nonsteroid anti-inflammatory drops
nonsteroid anti-inflammatory drops plus artificial tear substitute
nonsteroid anti-inflammatory drops
nonsteroid anti-inflammatory drops plus artificial tear substitute
corticosteroids
corticosteroids plus artificial tear substitute
artificial tear substitute
artificial tear substitute alone
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* tear film breakup time \>0 second and ≤5 seconds,or schirmer test(no anaesthesia)≥2mm/5min and ≤5mm/5min
* corneal staining≥3 scores
Exclusion Criteria
* previous use of anti-inflammatory drugs or immunosuppressive agent
* viral,bacterial or fungal infection of the eye
* eyelid anomaly
* glaucoma or high IOP
* significant meibomian gland dysfunction
18 Years
70 Years
ALL
No
Sponsors
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Wenzhou Medical University
OTHER
Responsible Party
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Xiangtian Zhou
MD
Principal Investigators
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Wei Chen, MD,PhD
Role: PRINCIPAL_INVESTIGATOR
Eye Hospital, Wenzhou Medical College, China
Locations
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Eye Hospital, Wenzhou Medical College
Wenzhou, Zhejiang, China
Countries
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Other Identifiers
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Xzhou
Identifier Type: -
Identifier Source: org_study_id
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