Albumin Use in Burn Patients

NCT ID: NCT00609414

Last Updated: 2011-04-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

460 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-01-31

Study Completion Date

2008-10-31

Brief Summary

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This is a study of why and how physicians use albumin during the first 72 hours after a burn injury.

Detailed Description

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While albumin has been a part of burn resuscitation for many years, its use remains varied and controversial. The purpose of this study is to describe the current practices of albumin administration during the first 72 hours after a burn injury. Participating sites will collect data on patients with at least a 20% Total Body Surface Area (TBSA) burn. Information will be recorded on type and extent of burn injury, basic demographic data, co-morbidities, outcomes and, for the first 72 hours post injury, if albumin was used and why, amount of resuscitation fluids and urine output, and use of vasopressors and diuretics.

Each participating site will retrospectively review 20 charts of consecutive admissions with at least a 20% TBSA burn. In addition, each site will collect data prospectively on 20 more patients with 20% TBSA burns. Prospective data is requested in order to capture as close as possible to "real time" the reasons physicians choose to give albumin. No Protected Health Information (PHI) will be recorded.

Data will be analyzed for patterns of albumin use and reasons for albumin administration.

Conditions

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Burns

Study Design

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Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Burn Injury, with and without inhalation injury

Exclusion Criteria

* \<20% Total Body Surface Area Burned
* Comfort care only for the burn injury
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of North Carolina, Chapel Hill

OTHER

Sponsor Role lead

Responsible Party

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Department of Surgery, University of North Carolina at Chapel Hill

Principal Investigators

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Bruce A. Cairns, MD

Role: PRINCIPAL_INVESTIGATOR

North Carolina Jaycee Burn Center, University of North Carolina Hospitals

Locations

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Arizona Burn Center, Maricopa Medical Center

Phoenix, Arizona, United States

Site Status

Bothin Burn Center, Saint Francis Memorial Hospital

San Francisco, California, United States

Site Status

Shands at the University of Florida Burn Center

Gainesville, Florida, United States

Site Status

Joseph M Still Research Foundation Inc and Doctors Hospital of Augusta

Augusta, Georgia, United States

Site Status

Bothin Burn Center, University of Kansas Hospital

Kansas City, Kansas, United States

Site Status

Regions Hospital Burn Center

Saint Paul, Minnesota, United States

Site Status

North Carolina Jaycee Burn Center, University of North Carolina Hospitals

Chapel Hill, North Carolina, United States

Site Status

Paul and Carol David Foundation Burn Institute, Akron Children's Hospital

Akron, Ohio, United States

Site Status

Shriners Hospitals for Children

Cincinnati, Ohio, United States

Site Status

Oregon Burn Center, Legacy Health System

Portland, Oregon, United States

Site Status

University of Utah Hospitals Burn Center

Salt Lake City, Utah, United States

Site Status

Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada

Site Status

Countries

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United States Canada

Other Identifiers

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04-1392

Identifier Type: -

Identifier Source: org_study_id

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