ASA- and Clopidogrel-Responsiveness in Patients With Peripheral Arterial Occlusive Disease and Interventional Procedures

NCT ID: NCT00593762

Last Updated: 2010-03-16

Basic Information

• Recruitment Status: SUSPENDED
• Total Enrollment: 200 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2005-05-31
• Study Completion Date: 2009-12-31

Brief Summary

The purpose of the study is to determine the response to aspirin (ASA) and Clopidogrel in patients with peripheral arterial occlusive disease (PAOD) requiring interventional procedures and to investigate if patients with "resistance" to ASA or Clopidogrel have an unfavourable outcome during long-term follow-up

Conditions

Peripheral Arterial Occlusive Disease

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• PAOD patients
• Age 18-85 years
• Need for a catheter interventional procedure
• Antithrombotic therapy with aspirin or clopidogrel

Exclusion Criteria

• Comedication additionally compromising platelet function
• Known bleeding disorder
• Life expectancy < 6 months

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Johann Wolfgang Goethe University Hospital

OTHER

Sponsor Role: lead

Responsible Party

Division of Vascular Medicine, Department of Internal Medicine, J.W.Goethe University Hospital Frankfurt

Principal Investigators

Birgit Linnemann, MD

Role: PRINCIPAL_INVESTIGATOR

Division of Vascular Medicine, Department of Internal Medicine, J.W. Goethe University Hospital Frankfurt

Locations

Division of Vascular Medicine, Department of Internal Medicine, J.W.Goethe University Hospital

Frankfurt am Main, Hesse, Germany

Countries

Germany

Other Identifiers

E 19/05

Identifier Type: -

Identifier Source: org_study_id