Incidence of Rhabdomyolysis Among Patients Admitted With Jimsonweed Ingestions

NCT ID: NCT00592657

Last Updated: 2008-07-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

46 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-01-31

Study Completion Date

2008-04-30

Brief Summary

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Retrospective chart review to determine the presence of rhabdomyolysis among patients admitted to CHMCA from 1997-2007 with Jimsonweed ingestions and to define possible risk factors predisposing patients to the developement of Jimsonweed-associated rhabdomyolysis.

Detailed Description

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Conditions

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Rhabdomyolysis Myoglobinuria Hemoglobinuria

Keywords

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retrospective chart review Jimsonweed ingestion

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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1

Patients diagnosed with rhabdomyolysis and no history of jimsonweed ingestion

No interventions assigned to this group

2

Patients diagnosed with rhabdomyolysis and history of jimsonweed ingestion

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* admitted to CHMCA between 1/1/1997 to 12/31/2007 with a qualifying ICD-9 diagnosis code for rhabdomyolysis, myoglobinuria, and hemoglobinuria (728.88, 791.2, 791.3)or other ICD-9 codes identified during the study
* between the ages of 0-21 years at diagnosis

Exclusion Criteria

* rhabdomyolysis or serum CK concentrations not actually documented
* patient admitted to the burn center
* patient \> 21 years of age
Maximum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Akron Children's Hospital

OTHER

Sponsor Role lead

Responsible Party

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CHMCA

Principal Investigators

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Martha Blackford

Role: PRINCIPAL_INVESTIGATOR

CHMCA

Locations

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Children's Hospital Medical Center of Akron

Akron, Ohio, United States

Site Status

Countries

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United States

References

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Forrester MB. Jimsonweed (Datura stramonium) exposures in Texas, 1998-2004. J Toxicol Environ Health A. 2006 Oct;69(19):1757-62. doi: 10.1080/15287390600631284.

Reference Type BACKGROUND
PMID: 16905506 (View on PubMed)

Ertekin V, Selimoglu MA, Altinkaynak S. A combination of unusual presentations of Datura stramonium intoxication in a child: rhabdomyolysis and fulminant hepatitius. J Emerg Med. 2005 Feb;28(2):227-8. doi: 10.1016/j.jemermed.2004.11.006. No abstract available.

Reference Type BACKGROUND
PMID: 15707824 (View on PubMed)

Giannoglou GD, Chatzizisis YS, Misirli G. The syndrome of rhabdomyolysis: Pathophysiology and diagnosis. Eur J Intern Med. 2007 Mar;18(2):90-100. doi: 10.1016/j.ejim.2006.09.020.

Reference Type BACKGROUND
PMID: 17338959 (View on PubMed)

Other Identifiers

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JIMSONWEED

Identifier Type: -

Identifier Source: org_study_id